Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Ultrasonic technologies in imaging and drug delivery

YJ Ho, CC Huang, CH Fan, HL Liu, CK Yeh - Cellular and Molecular Life …, 2021 - Springer
Ultrasonic technologies show great promise for diagnostic imaging and drug delivery in
theranostic applications. The development of functional and molecular ultrasound imaging is …

A novel gas embolotherapy using microbubbles electrocoalescence for cancer treatment

HA Sormoli, A Mojra, G Heidarinejad - Computer Methods and Programs in …, 2024 - Elsevier
Abstract Background and Objective Embolotherapy has been increasingly used to disrupt
tumor growth. Despite its success in the occlusion of microvessels, it has drawbacks such as …

Acoustic Droplet Vaporization of Perfluorohexane Emulsions Induced by Heterogeneous Nucleation at an Ultrasonic Frequency of 1.1 MHz

R Ramesh, C Thimonier, S Desgranges, V Faugeras… - Langmuir, 2023 - ACS Publications
Droplets made of liquid perfluorocarbon undergo a phase transition and transform into
microbubbles when triggered by ultrasound of intensity beyond a critical threshold; this …

Cellulose Nanofiber-Coated Perfluoropentane Droplets: Fabrication and Biocompatibility Study

K Loskutova, M Torras, Y Zhao, AJ Svagan… - International Journal …, 2023 - Taylor & Francis
Purpose To study the effect of cellulose nanofiber (CNF)-shelled perfluoropentane (PFP)
droplets on the cell viability of 4T1 breast cancer cells with or without the addition of non …

Investigation of the different parameters contributing to bubble sticking inside physiological bifurcations

R Salajeghe, MS Saidi - Medical & Biological Engineering & Computing, 2022 - Springer
Gas embolotherapy (GE) is a developing medical method which can be utilized either as an
autonomous therapeutic method to treat vascularized solid tumors, or it can be combined …

Ultrasound/radiation-responsive emulsions

G Calderó, G Paradossi - Current Opinion in Colloid & Interface Science, 2020 - Elsevier
The design of emulsions containing systems able to respond to different kinds of
perturbations is attracting increasing interest for biomedical purposes. Emulsions of phase …

[HTML][HTML] Combined gas embolization and chemotherapy can result in complete tumor regression in a murine hepatocellular carcinoma model

JS Harmon, F Kabinejadian, JL Bull - APL bioengineering, 2020 - pubs.aip.org
Hepatocellular carcinoma (HCC) is an intractable cancer with a high mortality rate.
Transarterial chemoembolization (TACE), a non-curative method, is the first line therapy for …

Direct Emulsification of Stable Superheated Perfluorobutane Nanodroplets by Sonication: Addressing the Limitations of the Microbubble Condensation Technique

A Woodward, RF Mattrey, C de Gracia Lux - Ultrasound in Medicine & …, 2024 - Elsevier
Objective We have previously determined that direct formulation of a phospholipid-based
perfluorobutane (PFB) emulsion using high-pressure homogenization produces …

Perfluorocarbon microdroplets stabilized by cellulose nanofibers: Toward ultrasound-mediated diagnostics and therapy

K Loskutova - 2023 - diva-portal.org
Ultrasound contrast agents consist of gas-filled micrometer-sized bubbles that are injected
into the blood stream. Ultrasound contrast agents are an invaluable tool for ultrasound …