Cumulative update of a systematic overview evaluating interventions addressing Polypharmacy

MS Keller, N Qureshi, AM Mays, CA Sarkisian… - JAMA Network …, 2024 - jamanetwork.com
Importance Polypharmacy is associated with mortality, falls, hospitalizations, and functional
and cognitive decline. The study of polypharmacy-related interventions has increased …

Decision-support systems for managing polypharmacy in the elderly: A scoping review

A Mouazer, R Tsopra, K Sedki, C Letord… - Journal of Biomedical …, 2022 - Elsevier
Polypharmacy, the consuming of more than five drugs, is a public health problem. It can lead
to many interactions and adverse drug reactions and is very expensive. Therapeutic …

Drinkable in situ-forming tough hydrogels for gastrointestinal therapeutics

GW Liu, MJ Pickett, JLP Kuosmanen, K Ishida… - Nature Materials, 2024 - nature.com
Pills are a cornerstone of medicine but can be challenging to swallow. While liquid
formulations are easier to ingest, they lack the capacity to localize therapeutics with …

Aging and the prevalence of polypharmacy and hyper-polypharmacy among older adults in South Korea: a national retrospective study during 2010–2019

HJ Cho, J Chae, SH Yoon, DS Kim - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Polypharmacy has become a global health problem and is associated with
adverse health outcomes in the elderly. This study evaluated the prevalence of …

The effect of polypharmacy on healthcare services utilization in older adults with comorbidities: a retrospective cohort study

G Doumat, D Daher, M Itani, L Abdouni, K El Asmar… - BMC Primary …, 2023 - Springer
Background Older adults are more prone to increasing comorbidities and polypharmacy.
Polypharmacy is associated with inappropriate prescribing and an increased risk of adverse …

Risk of polypharmacy and its outcome in terms of drug interaction in an elderly population: a retrospective cross-sectional study

RM Alhumaidi, GA Bamagous, SM Alsanosi… - Journal of Clinical …, 2023 - mdpi.com
The simultaneous use of multiple drugs—termed 'polypharmacy'—is often required to
manage multiple physiological and biological changes and the interplay between chronic …

Polypharmacy in multiple sclerosis: prevalence, risks, and mitigation strategies

WD Chapman, MC Herink, MH Cameron… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review Polypharmacy, the use of≥ 5 medications, is common in people
with multiple sclerosis and is associated with negative outcomes. The use of multiple …

Medication optimization protocol efficacy for geriatric inpatients: a randomized clinical trial

K Ie, M Hirose, T Sakai, I Motohashi, M Aihara… - JAMA network …, 2024 - jamanetwork.com
Importance There is currently no consensus on clinically effective interventions for
polypharmacy among older inpatients. Objective To evaluate the effect of multidisciplinary …

Drug utilisation review among geriatric patients with noncommunicable diseases in a primary care setting in Malaysia

P Manirajan, P Sivanandy - Healthcare, 2023 - mdpi.com
A prospective cross-sectional study was conducted to analyse the drugs prescribed to the
elderly population with noncommunicable diseases and to determine the polypharmacy at a …

A rapid review of interventions to improve medicine self‐management for older people living at home

G Previdoli, VL Cheong, D Alldred… - Health …, 2023 - Wiley Online Library
Background As people age, they are more likely to develop multiple long‐term conditions
that require complicated medicine regimens. Safely self‐managing multiple medicines at …