Phage diversity, genomics and phylogeny
Recent advances in viral metagenomics have enabled the rapid discovery of an
unprecedented catalogue of phages in numerous environments, from the human gut to the …
unprecedented catalogue of phages in numerous environments, from the human gut to the …
Molecular architecture of tailed double-stranded DNA phages
A Fokine, MG Rossmann - Bacteriophage, 2014 - Taylor & Francis
The tailed double-stranded DNA bacteriophages, or Caudovirales, constitute~ 96% of all the
known phages. Although these phages come in a great variety of sizes and morphology …
known phages. Although these phages come in a great variety of sizes and morphology …
The bacteriophage DNA packaging motor
An ATP-powered DNA translocation machine encapsidates the viral genome in the large
dsDNA bacteriophages. The essential components include the empty shell, prohead, and …
dsDNA bacteriophages. The essential components include the empty shell, prohead, and …
Structure and function of bacteriophage T4
ML Yap, MG Rossmann - Future microbiology, 2014 - Taylor & Francis
Bacteriophage T4 is the most well-studied member of Myoviridae, the most complex family of
tailed phages. T4 assembly is divided into three independent pathways: the head, the tail …
tailed phages. T4 assembly is divided into three independent pathways: the head, the tail …
Structure unifies the viral universe
NGA Abrescia, DH Bamford, JM Grimes… - Annual review of …, 2012 - annualreviews.org
Is it possible to meaningfully comprehend the diversity of the viral world? We propose that it
is. This is based on the observation that, although there is immense genomic variation, every …
is. This is based on the observation that, although there is immense genomic variation, every …
Automated classification of tailed bacteriophages according to their neck organization
Background The genetic diversity observed among bacteriophages remains a major
obstacle for the identification of homologs and the comparison of their functional modules. In …
obstacle for the identification of homologs and the comparison of their functional modules. In …
A common evolutionary origin for tailed-bacteriophage functional modules and bacterial machineries
D Veesler, C Cambillau - Microbiology and Molecular Biology …, 2011 - Am Soc Microbiol
Bacteriophages belonging to the order Caudovirales possess a tail acting as a molecular
nanomachine used during infection to recognize the host cell wall, attach to it, pierce it, and …
nanomachine used during infection to recognize the host cell wall, attach to it, pierce it, and …
Stochastic mechano-chemical kinetics of molecular motors: a multidisciplinary enterprise from a physicist's perspective
D Chowdhury - Physics Reports, 2013 - Elsevier
A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …
The DNA-packaging nanomotor of tailed bacteriophages
SR Casjens - Nature Reviews Microbiology, 2011 - nature.com
Tailed bacteriophages use nanomotors, or molecular machines that convert chemical
energy into physical movement of molecules, to insert their double-stranded DNA genomes …
energy into physical movement of molecules, to insert their double-stranded DNA genomes …
Structure and mechanism of DNA delivery of a gene transfer agent
Alphaproteobacteria, which are the most abundant microorganisms of temperate oceans,
produce phage-like particles called gene transfer agents (GTAs) that mediate lateral gene …
produce phage-like particles called gene transfer agents (GTAs) that mediate lateral gene …