Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy

S Kumari, R Gupta, RK Ambasta, P Kumar - Biochimica et Biophysica Acta …, 2023 - Elsevier
Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …

Mechanistic insights and the clinical prospects of targeted therapies for glioblastoma: a comprehensive review

Y Shen, DKH Thng, ALA Wong, TB Toh - Experimental Hematology & …, 2024 - Springer
Glioblastoma (GBM) is a fatal brain tumour that is traditionally diagnosed based on
histological features. Recent molecular profiling studies have reshaped the World Health …

YB-1 activating cascades as potential targets in KRAS-mutated tumors

S Khozooei, S Veerappan, M Toulany - Strahlentherapie und Onkologie, 2023 - Springer
Abstract Y‑box binding protein‑1 (YB-1) is a multifunctional protein that is highly expressed
in human solid tumors of various entities. Several cellular processes, eg cell cycle …

Emerging Therapies in Kirsten Rat Sarcoma Virus (+) Non-Small-Cell Lung Cancer

A Karachaliou, E Kotteas, O Fiste, K Syrigos - Cancers, 2024 - mdpi.com
Simple Summary Cancer is a heterogeneous disease characterized by uncontrollable
abnormal cell growth. KRAS plays a crucial role in cell proliferation and differentiation …

MicroRNA 452 regulates SHC1 expression in human colorectal cancer and colitis

J Mo, S Lamichhane, K Yun, SC Chae - Genes & Genomics, 2023 - Springer
Abstract Background Human microRNA 452 (MIR452) has been linked to both colorectal
cancer (CRC) tissues and dextran sulfate sodium (DSS)-induced colitis. Objective We …

Piperine inhibits the proliferation of colorectal adenocarcinoma by regulating ARL3-mediated endoplasmic reticulum stress

C Wu, Y Qian, J Jiang, D Li, L Feng - Biomolecules and Biomedicine, 2024 - bjbms.org
Colorectal adenocarcinoma (COAD) is a significant cause of cancer-related mortality
worldwide, necessitating the identification of novel therapeutic targets and treatments. This …

Features of obtaining and prospects for the use of colorectal tumor organoids

MG Krasnova, AS Efremova, TB Bukharova… - Genes & Cells, 2022 - genescells.ru
The review summarizes innovative advances in the field of organoids as a tool for accurate
cancer modeling. The conditions for reproducing the microenvironment in vitro based on …