Research into aging constitutes a pivotal endeavor aimed at elucidating the underlying
biological mechanisms governing aging and age-associated diseases, as well as promoting …

The molecular organization of the human neocortex historically has been studied in the
context of its histological layers. However, emerging spatial transcriptomic technologies …

Suicide is the second leading cause of death in US adolescents and young adults, and
generally associated with a psychiatric disorder. Suicidal behavior has a complex etiology …

The increase in publicly available human single-cell datasets, encompassing millions of
cells from many donors, has significantly enhanced our understanding of complex biological …

Reactive oxygen species (ROS) and oxidative stress accelerate cellular aging, but their
impact on different tissues varies. The cornea, known for its robust antioxidant defense …

Spatial transcriptomics has transformed genomic research by measuring spatially resolved
gene expressions, allowing us to investigate how cells adapt to their microenvironment via …

Genetic research has contributed greatly to the molecular diagnostics of
neurodevelopmental and neuropsychiatric disorders. Nevertheless, the precise molecular …

单细胞精度的表达数量性状位点研究进展 Page 1 Hereditas (Beijing) www.chinagene.cn 收稿
日期: 2024-06-05; 修回日期: 2024-08-30; 网络发布日期:2024-09-13 基金项目: 国家自然科学 …

The interaction between genetic variants and environmental stressors is key to
understanding the mechanisms underlying neurological diseases. In this study, we used …

Detailed knowledge of transcriptional responses to environmental and developmental cues
is impossible without single cell (SC) resolution data. We performed two SC RNAseq …