Insular glioma surgery: an evolution of thought and practice: JNSPG 75th Anniversary Invited Review Article

SL Hervey-Jumper, MS Berger - Journal of neurosurgery, 2019 - thejns.org
OBJECTIVE The goal of this article is to review the history of surgery for low-and high-grade
gliomas located within the insula with particular focus on microsurgical technique …

[HTML][HTML] Management of epilepsy in brain tumor patients

PB Van der Meer, MJB Taphoorn… - Current opinion in …, 2022 - journals.lww.com
Management of epilepsy in brain tumor patients : Current Opinion in Oncology Management
of epilepsy in brain tumor patients : Current Opinion in Oncology Log in or Register Subscribe …

[HTML][HTML] Postoperative risk of IDH-mutant glioma–associated seizures and their potential management with IDH-mutant inhibitors

MR Drumm, W Wang, TK Sears… - The Journal of …, 2023 - Am Soc Clin Investig
Seizures are a frequent complication of adult-type diffuse gliomas, and are often difficult to
control with medications. Gliomas with mutations in isocitrate dehydrogenase 1 or 2 …

Diffuse low-grade glioma-related epilepsy

J Pallud, GM McKhann - Neurosurgery Clinics, 2019 - neurosurgery.theclinics.com
Epileptic seizures are iconic symptomatic expressions of cerebral gliomas. 1 The origin and
mechanisms of human glioma-related epilepsy are multifactorial, intermixed within the same …

TXNDC12 knockdown promotes ferroptosis by modulating SLC7A11 expression in glioma

H Yu, K Zhu, M Wang, X Jiang - Clinical and Translational …, 2023 - Wiley Online Library
Ferroptosis is an iron‐dependent cell death process mainly triggered by reactive oxygen
species (ROS) and lipid peroxidation. Thioredoxin domain protein 12 (TXNDC12) promotes …

Using quicktome for intracerebral surgery: early retrospective study and proof of concept

JT Yeung, HM Taylor, PJ Nicholas, IM Young, I Jiang… - World neurosurgery, 2021 - Elsevier
Background Neurosurgeons have limited tools in their armamentarium to visualize critical
brain networks during surgical planning. Quicktome was designed using machine-learning …

[HTML][HTML] Challenging giant insular gliomas with brain mapping: evaluation of neurosurgical, neurological, neuropsychological, and quality of life results in a large …

M Rossi, L Gay, M Conti Nibali, T Sciortino… - Frontiers in …, 2021 - frontiersin.org
Objective Giant insular tumors are commonly not amenable to complete resection and are
associated with a high postoperative morbidity rate. Transcortical approach and brain …

Recurrent insular low-grade gliomas: factors guiding the decision to reoperate

L Ribeiro, S Ng, H Duffau - Journal of Neurosurgery, 2022 - thejns.org
OBJECTIVE Reoperation has been established as an effective therapeutic strategy in
recurrent diffuse low-grade gliomas (LGGs). Insular gliomas represent a specific surgical …

Functional mapping for glioma surgery, part 2: intraoperative mapping tools

RA Morshed, JS Young, AT Lee… - Neurosurgery …, 2021 - neurosurgery.theclinics.com
Surgical resection is a mainstay of treatment for patients who are diagnosed with a
presumed glioma, even when involving areas of the brain with presumed functional …

Perioperative outcomes following reoperation for recurrent insular gliomas

RA Morshed, JS Young, SJ Han… - Journal of …, 2018 - thejns.org
OBJECTIVE Greater extent of resection (EOR) improves overall survival and progression-
free survival for patients with low-and high-grade glioma. While resection for newly …