Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Defect engineering of layered double hydroxide nanosheets as inorganic photosensitizers for NIR-III photodynamic cancer therapy

W Shen, T Hu, X Liu, J Zha, F Meng, Z Wu, Z Cui… - Nature …, 2022 - nature.com
Abstract Although two-dimensional (2D) layered double hydroxides (LDHs) have been
widely used as efficient nanoagents for biological diagnosis and treatment, they have been …

Photodecaging of a mitochondria-localized iridium (III) endoperoxide complex for two-photon photoactivated therapy under hypoxia

S Kuang, F Wei, J Karges, L Ke, K Xiong… - Journal of the …, 2022 - ACS Publications
Despite the clinical success of photodynamic therapy (PDT), the application of this medical
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …

Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments

M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

[HTML][HTML] Combined photodynamic and photothermal therapy and immunotherapy for cancer treatment: a review

C Kong, X Chen - International journal of nanomedicine, 2022 - ncbi.nlm.nih.gov
Photoactivation therapy based on photodynamic therapy (PDT) and photothermal therapy
(PTT) has been identified as a tumour ablation modality for numerous cancer indications …

An NIR Discrete Metallacycle constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for imaging‐guided cancer Radio‐chemotherapy

Y Ding, Z Tong, L Jin, B Ye, J Zhou, Z Sun… - Advanced …, 2022 - Wiley Online Library
To promote the clinical theranostic performances of platinum‐based anticancer drugs,
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …

Improving image‐guided surgical and immunological tumor treatment efficacy by photothermal and photodynamic therapies based on a multifunctional NIR AIEgen

R Jiang, J Dai, X Dong, Q Wang, Z Meng… - Advanced …, 2021 - Wiley Online Library
Multimodal therapy is attracting increasing attention to improve tumor treatment efficacy, but
generally requires various complicated ingredients combined within one theranostic system …

A Metal‐Free Mesoporous Carbon Dots/Silica Hybrid Type I Photosensitizer with Enzyme‐Activity for Synergistic Treatment of Hypoxic Tumor

B Tian, S Liu, C Yu, S Liu, S Dong… - Advanced Functional …, 2023 - Wiley Online Library
As a less O2‐dependent photodynamic therapy (PDT), type I PDT is an effective approach to
overcome the hypoxia‐induced low efficiency against solid tumors. However, the commonly …

Singlet oxygen “afterglow” therapy with NIR‐II fluorescent molecules

J Zou, L Li, J Zhu, X Li, Z Yang, W Huang… - Advanced …, 2021 - Wiley Online Library
Abstract Improving singlet oxygen (1O2) lifespan by fractionated delivery in dark and
hypoxic conditions is a better way to achieve enhanced phototherapeutic efficacy. Herein …