The assembly of just a single kinetochore at the centromere of each sister chromatid is
essential for accurate chromosome segregation during cell division. Surprisingly, despite …

Since the discovery of the first human neocentromere in 1993, these spontaneous, ectopic
centromeres have been shown to be an astonishing example of epigenetic change within …

Motivation: Redundant protein sequences in biological databases hinder sequence
similarity searches and make interpretation of search results difficult. Clustering of protein …

The plant genome is organized into chromosomes that provide the structure for the genetic
linkage groups and allow faithful replication, transcription and transmission of the hereditary …

Centromeres in most higher eukaryotes are composed of long arrays of satellite repeats. By
contrast, most newly formed centromeres (neocentromeres) do not contain satellite repeats …

We present high-resolution maps of DNA methylation and H3K4 di-and trimethylation of two
entire chromosomes and two fully sequenced centromeres in rice (Oryza sativa) shoots and …

The evolutionary history of chromosomes can be tracked by the comparative hybridization of
large panels of bacterial artificial chromosome clones. This approach has disclosed an …

Identification of all expressed transcripts in a sequenced genome is essential both for
genome analysis and for realization of the goals of systems biology. We used the …

The centromere in eukaryotes is defined by the presence of a special histone H3 variant,
CENH3. Centromeric chromatin consists of blocks of CENH3-containing nucleosomes …

The pericentromere and centromere regions of the genome have previously been
considered tightly compacted and transcriptionally inert. However, there is mounting …