Design, synthesis, biological evaluation of 3, 5-diaryl-4, 5-dihydro-1H-pyrazole carbaldehydes as non-purine xanthine oxidase inhibitors: Tracing the anticancer …

G Joshi, M Sharma, S Kalra, NS Gavande, S Singh… - Bioorganic …, 2021 - Elsevier
Xanthine oxidase (XO) has been primarily targeted for the development of anti-
hyperuriciemic/anti-gout agents as it catalyzes the conversion of xanthine and hypoxanthine …

Anti-tumor alkaloids from Peganum harmala

Q Zhang, YH Zan, HG Yang, MY Yang, FS Liu, SG Li… - Phytochemistry, 2022 - Elsevier
Six alkaloids peharmalines F–K, along with 14 known ones, were isolated from the aerial
part of Peganum harmala L.. The structures of the isolated compounds were determined …

Peganum harmala L.: A Review of Botany, Traditional Use, Phytochemistry, Pharmacology, Quality marker, and Toxicity

LN Li - Combinatorial Chemistry & High Throughput Screening, 2024 - ingentaconnect.com
Background: Peganum harmala L. is a perennial herb of Peganum in Zygophyllaceae
family. It has been used as a national medicinal herb with the efficacy of strengthening …

Design, Synthesis and Biological Evaluation of New 5‐(2‐Nitrophenyl)‐1‐aryl‐1H‐pyrazoles as Topoisomerase Inhibitors

M Kaur, V Mehta, S Arora, A Munshi, S Singh… - …, 2021 - Wiley Online Library
(2‐Nitrophenyl)‐1‐aryl‐1H‐pyrazoles are designed as topoisomerase (Topo) inhibitors,
synthesised and assessed for their anticancer properties against breast (MDA‐MB‐231 and …

Synthesis of Quinoline and Quinolin-2 (1H)-one Derivatives via Nickel Boride Promoted Reductive Cyclization

R Sarkar, SK Samanta, AM Menon, D Chopra… - …, 2023 - thieme-connect.com
A mild and efficient approach for the synthesis of diversely substituted quinoline and
quinolin-2-one derivatives is disclosed. In situ generated nickel boride proved to be an …