The blood that flows perpetually through our veins and arteries performs numerous functions
essential to our survival. Besides distributing oxygen, this vast circulatory system facilitates …

Background The role of the human microbiome in health and disease is an emerging and
important area of research; however, there is a concern that African populations are under …

The characterization of the blood virome is important for the safety of blood-derived
transfusion products, and for the identification of emerging pathogens. We explored non …

In 2017, the order Mononegavirales was expanded by the inclusion of a total of 69 novel
species. Five new rhabdovirus genera and one new nyamivirus genus were established to …

Effective infectious disease surveillance in high-risk regions is critical for clinical care and
pandemic preemption; however, few clinical diagnostics are available for the wide range of …

Metagenomic sequencing has the potential to transform microbial detection and
characterization, but new tools are needed to improve its sensitivity. Here we present …

High-throughput sequencing technologies have revolutionized how we think about viruses.
Investigators can now go beyond pathogenic viruses and have access to the thousands of …

Human blood metagenomics has revealed the presence of different types of viruses in
apparently healthy subjects. By far, anelloviruses constitute the viral family that is more …

The human virome is composed by the set of all viruses, eukaryotic and prokaryotic, present
in the human body; as each body compartment constitutes a different microenvironment, the …

Background Metagenomic next-generation sequencing (mNGS) has emerged as a
promising technology that enables pan-pathogen detection from any source. However …