Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …

Although the assortment of antifungal drugs is broad, the most commonly used agents have
major drawbacks. Toxicity, serious side effects or the emergence of drug resistance are …

Lipophilicity is one of many parameters involved in the biological activity of drugs, as it
affects their pharmacokinetic and pharmacodynamic behavior. Generally, lipophilicity is …

Introduction: Bacteriological infections are a major risk to human health. These include all
hospital and public-acquired infections. In drug discovery, rhodanines are privileged …

N-ribosylation and N-mannosylation compounds have a great role in compounds activity as
anticancer. The reaction of 2-thioxo-4-thiazolidinone (rhodanine) derivatives, as aglycon …

Abstract Twenty-four 2-(4-oxo-2-thioxothiazolidin-3-yl) acetic acid (rhodanine-3-acetic acid)-
based amides, esters and 5-arylalkylidene derivatives were synthesized, characterized and …

Based on a broad spectrum of biological activities of rhodanines, we synthesized aromatic
amides and esters of 2-(4-oxo-2-thioxothiazolidin-3-yl) acetic acid (rhodanine-3-acetic acid) …

The solvent-free condensation reaction of various aliphatic aldehydes, cycloalkanones, and
benzaldehydes with rhodanines catalyzed by Amberlyst 26 has been reported. The …

Substituted piperazine and aniline derivatives of oxazolidin-2, 4-diones and imidazolidin-2,
4-diones were synthesized by N 3 alkylation and screened for their anticonvulsant activity by …

Nitrogen and sulfur glycosylation was carried out via the reaction of rhodanine (1) with α-
acetobromoglucose 3 under basic conditions. Deacetylation of the protected nitrogen …