Epidemiology of multiple sclerosis: from risk factors to prevention—an update

A Ascherio, KL Munger - Seminars in neurology, 2016 - thieme-connect.com
Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within
families and the sharp decline in risk with increasing genetic distance, it cannot fully explain …

The gut microbiota in multiple sclerosis: an overview of clinical trials

G Schepici, S Silvestro, P Bramanti… - Cell …, 2019 - journals.sagepub.com
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating, and degenerative disease
that affects the central nervous system. A recent study showed that interaction between the …

Vitamin D as an early predictor of multiple sclerosis activity and progression

A Ascherio, KL Munger, R White, K Köchert… - JAMA …, 2014 - jamanetwork.com
Importance It remains unclear whether vitamin D insufficiency, which is common in
individuals with multiple sclerosis (MS), has an adverse effect on MS outcomes. Objectives …

[HTML][HTML] Vitamin D and neurological diseases: an endocrine view

C Di Somma, E Scarano, L Barrea… - International journal of …, 2017 - mdpi.com
Vitamin D system comprises hormone precursors, active metabolites, carriers, enzymes, and
receptors involved in genomic and non-genomic effects. In addition to classical bone-related …

Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop

MP Amato, T Derfuss, B Hemmer… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Multiple sclerosis (MS) is an inflammatory and neurodegenerative demyelinating disease of
the central nervous system (CNS), most likely autoimmune in origin, usually beginning in …

Randomized trial of daily high-dose vitamin D3 in patients with RRMS receiving subcutaneous interferon β-1a

R Hupperts, J Smolders, R Vieth, T Holmøy… - Neurology, 2019 - AAN Enterprises
Objective In the phase II, randomized, double-blind, placebo-controlled Supplementation of
Vigantol Oil versus Placebo Add-on in Patients with Relapsing-Remitting Multiple Sclerosis …

Multiple sclerosis relapses: epidemiology, outcomes and management. A systematic review

T Kalincik - Neuroepidemiology, 2015 - karger.com
Relapses (episodic exacerbations of neurological signs or symptoms) are a defining feature
of relapsing-remitting multiple sclerosis (MS), the most prevalent MS phenotype. While their …

Vitamin D for the management of multiple sclerosis

VA Jagannath, G Filippini… - Cochrane database …, 2018 - cochranelibrary.com
Background This review is an update of a previously published review," Vitamin D for the
management of multiple sclerosis"(published in the Cochrane Library; 2010, Issue 12) …

Treatment optimization in MS: Canadian MS Working Group updated recommendations

MS Freedman, D Selchen, DL Arnold, A Prat… - Canadian Journal of …, 2013 - cambridge.org
The Canadian Multiple Sclerosis Working Group (CMSWG) developed practical
recommendations in 2004 to assist clinicians in optimizing the use of disease-modifying …

Safety and immunologic effects of high-vs low-dose cholecalciferol in multiple sclerosis

ES Sotirchos, P Bhargava, C Eckstein, K Van Haren… - Neurology, 2016 - AAN Enterprises
Objective: To study the safety profile and characterize the immunologic effects of high-vs low-
dose cholecalciferol supplementation in patients with multiple sclerosis (MS). Methods: In …