[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection

BA Khalil, NM Elemam, AA Maghazachi - Computational and structural …, 2021 - Elsevier
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
SARS-COV-2 infection represents the greatest pandemic of the world, counting daily
increasing number of subjects positive to the virus and, sadly, increasing number of deaths …

Global absence and targeting of protective immune states in severe COVID-19

AJ Combes, T Courau, NF Kuhn, KH Hu, A Ray… - Nature, 2021 - nature.com
Although infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
pleiotropic and systemic effects in some individuals,–, many others experience milder …

The cytokines HGF and CXCL13 predict the severity and the mortality in COVID-19 patients

M Perreau, M Suffiotti, P Marques-Vidal… - Nature …, 2021 - nature.com
The objective of the present study was to identify biological signatures of severe coronavirus
disease 2019 (COVID-19) predictive of admission in the intensive care unit (ICU). Over 170 …

Longitudinal cytokine profile in patients with mild to critical COVID-19

L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …

Innate receptor activation patterns involving TLR and NLR synergisms in COVID-19, ALI/ARDS and sepsis cytokine storms: a review and model making novel …

R Root-Bernstein - International journal of molecular sciences, 2021 - mdpi.com
Severe COVID-19 is characterized by a “cytokine storm”, the mechanism of which is not yet
understood. I propose that cytokine storms result from synergistic interactions among Toll …

SARS-COV-2-related immune-inflammatory thyroid disorders: facts and perspectives

RM Ruggeri, A Campennì, D Deandreis… - Expert review of …, 2021 - Taylor & Francis
Introduction: During the COVID-19 pandemic thyroid gland alteration/dysfunction has been
emerged as a possible endocrine complication. The present review is focused on …

The cytokine storm and thyroid hormone changes in COVID-19

L Croce, D Gangemi, G Ancona, F Liboà… - Journal of …, 2021 - Springer
Background COVID-19 is now a worldwide pandemic. Among the many extra-pulmonary
manifestations of COVID-19, recent evidence suggested a possible occurrence of thyroid …

SARS-CoV-2: emerging role in the pathogenesis of various thyroid diseases

AK Murugan, AS Alzahrani - Journal of Inflammation Research, 2021 - Taylor & Francis
Abstract Coronavirus disease-2019 (COVID-19) is asymptomatic in most cases, but it is
impartible and fatal in fragile and elderly people. Heretofore, more than four million people …

CXCL10 chemokine: a critical player in RNA and DNA viral infections

NM Elemam, IM Talaat, AA Maghazachi - Viruses, 2022 - mdpi.com
Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …