Stem cells can be defined as units of biological organization that are responsible for the
development and the regeneration of organ and tissue systems. They are able to renew their …

BACKGROUND In adult mammalian organisms, multiple tissues—including the skin, blood,
stomach, and intestines—are entrapped in a state of permanent regeneration; older cells are …

Haematopoietic stem cells (HSCs) are a rare cell type that reconstitute the entire blood and
immune systems after transplantation and can be used as a curative cell therapy for a variety …

Due to the adverse effects of erythropoietin (EPO) on cancer patient survival, it is necessary
to develop new agents that can be used to efficiently manage and treat cancer‐related …

Regulation of hematopoiesis during human development remains poorly defined. Here we
applied single-cell RNA sequencing (scRNA-seq) and single-cell assay for transposase …

Stem cells are highly resistant to viral infection compared to their differentiated progeny;
however, the mechanism is mysterious. Here, we analyzed gene expression in mammalian …

Haematopoietic stem cells (HSCs) are widely studied by HSC transplantation into immune-
and blood-cell-depleted recipients. Single HSCs can rebuild the system after …

Background Extracellular matrix (ECM) is a dynamic and complex environment
characterized by biophysical, mechanical and biochemical properties specific for each …

It is currently thought that life-long blood cell production is driven by the action of a small
number of multipotent haematopoietic stem cells. Evidence supporting this view has been …

Periodontium is consisted of root cementum, bone lining the tooth socket, gingiva facing the
tooth, and periodontal ligament (PDL). Its primary functions are support of the tooth and …