An increase in the fast blood glucose (FBG) levels has been linked to an increased risk of
developing a chronic condition, type 2 diabetes (T2D). The mutation in the G6PC2 gene was …

K-Ras mutations are frequent in various cancer types, and according to recent research, K-
Ras possesses four-drug targeting sites. This increased our interest in finding potential small …

Amid the ongoing monkeypox outbreak, there is an urgent need for the rapid development of
effective therapeutic interventions capable of countering the immune evasion mechanisms …

The mutations at the hotspot region of K‐Ras result in the progression of cancer types. Our
study aimed to explore the small molecule inhibitors against the G13D mutant K‐Ras model …

Glycosylation is recognized as a key process for proper megakaryopoiesis and platelet
formation. The enzyme uridine diphosphate (UDP)-galactose-4-epimerase, encoded by …

The vital tissue homeostasis regulator p53 forms a tetramer when it binds to DNA and
regulates the genes that mediate essential biological processes such as cell-cycle arrest …

Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly used in clinical
practice for the management of type 2 diabetes mellitus. However, the extremely short half …

Background: Mutations in the K-Ras gene are among the most frequent genetic alterations
in various cancers, and inhibiting RAS signaling has shown promising results in treating …

Stüve-Wiedemann syndrome (SWS), a rare autosomal recessive disorder, characterized by
diminutive size, curvature of the elongated bones, bent fingers, episodes of heightened body …

The human transmembrane protease serine 2 (TMPRSS2) protein plays an important role in
prostate cancer progression. It also facilitates viral entry into target cells by proteolytically …