Pediatric acute myeloid leukemia is a rare and heterogeneous disease in relation to
morphology, immunophenotyping, germline and somatic cytogenetic and genetic …

Simple Summary Cryopreservation of ovarian tissue and transplantation are the only
available fertility techniques to preserve fertility and endocrine function for prepubertal girls …

The genetics of relapsed pediatric acute myeloid leukemia (AML) has yet to be
comprehensively defined. Here, we present the spectrum of genomic alterations in 136 …

The pseudokinase Trib1 functions as a myeloid oncogene that recruits the E3 ubiquitin
ligase COP1 to C/EBPα and interacts with MEK1 to enhance extracellular signal-regulated …

Genomic characterization of pediatric patients with acute myeloid leukemia (AML) has led to
the discovery of somatic mutations with prognostic implications. Although gene-expression …

Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) following
chemotherapy is part of standard treatment protocol for patients with acute myeloid leukemia …

Elucidating genetic aberrations in pediatric acute myeloid leukemia (AML) provides insight
in biology and may impact on risk-group stratification and clinical outcome. This study aimed …

Allogeneic hematopoietic stem cell transplantation (HSCT) offers potentially curative
treatment for many children with high-risk or relapsed acute leukemia (AL), thanks to the …

Introduction: Trisomy 8 is one of the most common cytogenetic alterations in acute myeloid
leukemia (AML), with a frequency between 10% and 15%. Areas covered: The authors …

Pediatric acute myeloid leukemia (AML) is a heterogeneous disease that requires a
multifaceted treatment approach. Although outcomes for low‐risk AML have improved …