The nonradiative conversion of light energy into heat (photothermal therapy, PTT) or sound
energy (photoacoustic imaging, PAI) has been intensively investigated for the treatment and …

The life sciences can benefit greatly from imaging technologies that connect microscopic
discoveries with macroscopic observations. One technology uniquely positioned to provide …

Vibrational spectroscopy is a ubiquitous technology that derives the species, constituents
and morphology of an object from its natural vibrations. However, natural vibrations of …

Visualization of dynamic functional and molecular events in an unperturbed in vivo
environment is essential for understanding the complex biology of living organisms and of …

Conventional medical imaging technologies, including ultrasound, have continued to
improve over the years. For example, in oncology, medical imaging is characterized by high …

Fuelled by innovation, optical microscopy plays a critical role in the life sciences and
medicine, from basic discovery to clinical diagnostics. However, optical microscopy is limited …

Cell mechanical properties, eg elastic and shear modulus, play vital roles in cell activities
and functions, such as cell growth, cell division, cell motion, and cell adhesion …

Photoacoustic imaging has experienced exponential growth over the past decade, with
many applications in biomedicine. One application ideally suited to the analysis of single …

Optical resolution photoacoustic microscopy (OR-PAM) is a non-invasive, label-free method
of in vivo imaging with microscopic resolution and high optical contrast. Based on intrinsic …

Photoacoustic measurements of melanoma cells and red blood cells (RBCs) using ultra-
high frequency (UHF) wide-bandwidth transducers are reported. In this detection system, the …