The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …

Neuroinflammatory mediators play a crucial role in the pathophysiology of brain ischemia,
exerting either deleterious effects on the progression of tissue damage or beneficial roles …

Ischemic cerebral stroke is a major cause of death and morbidity. Currently, no
neuroprotective agents have been shown to impact the clinical outcomes in cerebral stroke …

Abstract Background Elevated plasma homocysteine (Hcy) levels have been indicated as a
strong and modifiable risk factor of ischemic stroke; the previous studies have shown that …

MicroRNAs (miRNAs) are∼ 22 nucleotides long, noncoding RNAs that control cellular
function by either degrading mRNAs or arresting their translation. To understand their …

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors of the nuclear hormone receptor superfamily. The 3 PPAR isoforms (alpha, delta/beta …

Background: Subtypes of microglia/macrophage regulate the inflammation in the opposite
direction during ischemic stroke. JAK2/STAT3 signaling pathway participates in the …

Objective Contribution of individual and combined inflammatory markers in prognosis after
stroke was still undefined. We aimed to investigate the association of systemic and local …

Background Microglia/macrophages are activated after cerebral ischemic stroke and can
contribute to either brain injury or recovery by polarizing microglia/macrophage into …

Cerebral stroke is ranked as the third most common contributor to global mortality and
disability. The involvement of inflammatory mechanisms, both peripherally and within the …