Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …

Recent progressions in immunotherapy have transformed cancer treatment, providing a
promising strategy that activates the immune system of the patient to find and eliminate …

Background Chimeric antigen receptor (CAR)-T cell therapy is an efficient therapeutic
strategy for specific hematologic malignancies. However, positive outcomes of this novel …

Context Prostate-specific membrane antigen (PSMA) is a promising, novel theranostic target
in advanced prostate cancer (PCa). Multiple PSMA-targeted therapies are currently in …

Introduction The development of long-acting injectables (LAIs) for protein and peptide
therapeutics has been a key challenge over the last 20 years. If these molecules offer …

Highlights•Immune cell engagers (ICEs) are molecules able to redirect immune effector cells
against cancer cells.•ICEs can be used for the redirection of T cells, natural killer (NK) cells …

Several therapeutic advancements in the treatment of B-cell acute lymphoblastic leukemia
(ALL) have surfaced in the past decade, primarily driven by an increased understanding of …

Bispecific antibodies (BsAbs)-based therapeutics have been identified to be one of the most
promising immunotherapy strategies. However, their target repertoire is mainly restricted to …

Immunotherapy has emerged as an important approach for cancer treatment, but its clinical
efficacy has been limited in prostate cancer compared to other malignancies. This review …