Drug repurposing for cancer therapy

Y Xia, M Sun, H Huang, WL Jin - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …

Proton pump inhibitors display anti‐tumour potential in glioma

B Li, Y Liu, S Sun - Cell Proliferation, 2023 - Wiley Online Library
Objectives Glioma is one of the most aggressive brain tumours with poor overall survival
despite advanced technology in surgical resection, chemotherapy and radiation …

Proton-pump inhibitor use amongst patients with severe hypomagnesemia

S Seah, YK Tan, K Teh, WJ Loh, PT Tan… - Frontiers in …, 2023 - frontiersin.org
Introduction: Long-term proton pump inhibitor (PPI) use has been associated with
hypomagnesemia. It is unknown how frequently PPI use is implicated in patients with severe …

[HTML][HTML] Assessment of adherence to the national stress ulcer prophylaxis guidelines: A cross-sectional analysis

SS Alhujilan, MS Saeed, AA Alalwan - Saudi Pharmaceutical Journal, 2023 - Elsevier
Background Clinical guidelines support the use of stress ulcer prophylaxis (SUP) in patients
at risk of gastrointestinal (GI) bleeding such as those with coagulopathy, renal replacement …

The impact of pharmacist intervention on the intravenous-to-oral switch therapy of proton pump inhibitors in cardiovascular surgery

J Bao, L Zhou, M Xu, J Ma - Expert Opinion on Drug Safety, 2023 - Taylor & Francis
Background The prescriptions of proton pump inhibitors (PPIs) have been widely concerned
due to both huge increase in medical costs and possible long-term adverse events (AEs) …

Myristica fragrans water extract modulates multiple biological processes to pre-protect anhydrous ethanol-induced gastric ulcers via Akt/JNK/Nrf2 pathway activation

X Li, J Wang, J Zhou, H Xiao, L Liu, Z Zhang, J Si… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Myristica fragrans (Nutmeg) is a commonly used Chinese
herbal medicine and edible spice. According to Pharmacopoeia of People's Republic of …

[HTML][HTML] The combined use of anti-peptic agents is associated with an increased risk of osteoporotic fracture: a nationwide case-control study

DJ Oh, JH Nam, HS Lee, YR Moon… - The Korean Journal of …, 2024 - ncbi.nlm.nih.gov
Methods A population-based case-control study was conducted by analyzing the Korean
National Health Insurance Data from 2014 to 2020. Patients who had been prescribed anti …

[HTML][HTML] Effects of proton pump inhibitors on inflammatory bowel disease: An updated review

Y Liang, Z Meng, XL Ding, M Jiang - World Journal of …, 2024 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is believed to be caused by various factors, including
abnormalities in disease susceptibility genes, environmental factors, immune factors, and …

[HTML][HTML] The Gastroprotective Effects of Anisomeles indica against Ethanol-Induced Gastric Ulcer through the Induction of IκB-α and the Inhibition of NF-κB Expression

YR Chen, HM Lien, FJ Tsai, JW Liao, YT Chen - Nutrients, 2024 - mdpi.com
Anisomeles indica (L.) Kuntze is a traditional herb with multiple medicinal properties and
with potential for preventing or treating various diseases. Acteoside, one of the active …

The therapeutic effect of different cumin essential oil fractions against gastric ulcer in rats

S Lu, F Suo, W Yu, G Wu - Journal of Food Science, 2024 - Wiley Online Library
Cumin, a popular spice, is widely used to treat stomach ailments in Central Asia and
Xinjiang, China. Cumin essential oil has been found to effectively treat gastric ulcers, but its …