[HTML][HTML] Current trends in gelatin-based drug delivery systems

F Milano, A Masi, M Madaghiele, A Sannino… - Pharmaceutics, 2023 - mdpi.com
Gelatin is a highly versatile natural polymer, which is widely used in healthcare-related
sectors due to its advantageous properties, such as biocompatibility, biodegradability, low …

Nonspherical nanoparticle shape stability is affected by complex manufacturing aspects: Its implications for drug delivery and targeting

BM Haryadi, D Hafner, I Amin… - Advanced …, 2019 - Wiley Online Library
The shape of nanoparticles is known recently as an important design parameter influencing
considerably the fate of nanoparticles with and in biological systems. Several manufacturing …

[HTML][HTML] Microfluidics as tool to prepare size-tunable PLGA nanoparticles with high curcumin encapsulation for efficient mucus penetration

N Lababidi, V Sigal, A Koenneke… - Beilstein Journal of …, 2019 - beilstein-journals.org
Great challenges still remain to develop drug carriers able to penetrate biological barriers
(such as the dense mucus in cystic fibrosis) and for the treatment of bacteria residing in …

Synthesis of pH responsive, photocrosslinked gelatin-based hydrogel system for control release of ceftriaxone

K Hussain, Z Aslam, S Ullah, MR Shah - Chemistry and Physics of Lipids, 2021 - Elsevier
Stimuli-responsive or smart nanocarriers are emerging class of materials used for drug
delivery and tissue engineering applications. The objective of this study was to develop …

Gelatin nanoparticles for NSAID systemic administration: Quality by design and artificial neural networks implementation

AE Koletti, E Tsarouchi, A Kapourani… - International Journal of …, 2020 - Elsevier
The present study evaluates the preparation of systemic administrated NSAID gelatin
nanoparticles with the aid of quality by design and artificial neural networks (ANNs) …

Sustained release biocompatible ocular insert using hot melt extrusion technology: fabrication and in-vivo evaluation

SA Khan, X Ma, SV Jermain, H Ali, IA Khalil… - Journal of Drug Delivery …, 2022 - Elsevier
Topical eye drops usually have low bioavailability of the drug. Rapid turnover of lacrimal
fluid flushes the drug away from the ocular surface, and the drug has limited time for …

Design and characterization of surface‐crosslinked gelatin nanoparticles for the delivery of hydrophilic macromolecular drugs

A Baseer, A Koenneke, J Zapp, SA Khan… - Macromolecular …, 2019 - Wiley Online Library
For nanotechnology enabled delivery of hydrophilic protein‐based drugs, several polymer‐
based carrier systems have been used in the past to protect the sensitive load and to …

NIR‐Emitting Gold Nanoclusters–Modified Gelatin Nanoparticles as a Bioimaging Agent in Tissue

N El‐Sayed, V Trouillet, A Clasen… - Advanced …, 2019 - Wiley Online Library
Gold nanocluster (AuNC) synthesis using a well‐distinguished polymer for nanoparticle‐
mediated drug delivery paves the way for developing efficient theranostics based on …

Preparation of maltodextrin nanoparticles and encapsulation of bovine serum albumin–Influence of formulation parameters

S Barthold, M Hittinger, D Primavessy, A Zapp… - European Journal of …, 2019 - Elsevier
Maltodextrin, which is obtained by partial hydrolysis of starch, is water soluble and could
serve as hydrophilic carrier for the encapsulation of protein-based active pharmaceutical …

Synthesis of fish gelatin nanoparticles and their application for the drug delivery based on response surface methodology

D Subara, I Jaswir, MFR Alkhatib… - Advances in Natural …, 2018 - iopscience.iop.org
Fish gelatin nanoparticle is produced using Tilapia fish skin for the first time by the two-step
desolvation method. Fish gelatin is chosen for producing gelatin nanoparticles because no …