While most studies of T lymphocytes have focused on T cells reactive to complexes of
peptide and major histocompatibility complex (MHC) proteins, many other types of T cells do …

Most studies on the immunotherapeutic potential of T cells have focused on CD8 and CD4 T
cells that recognize peptide antigens (Ag) presented by polymorphic major histocompatibility …

Natural killer T (NKT) cells are specialized CD1d-restricted T cells that recognize lipid
antigens. Following stimulation, NKT cells lead to downstream activation of both innate and …

Recent years have seen so-called natural killer T (NKT) cells emerge as important
regulators of the immune response. The existence of NKT-cell subsets, and other types of T …

▪ Abstract This review summarizes the major features of CD1 genes and proteins, the
patterns of intracellular trafficking of CD1 molecules, and how they sample different …

CD1d-restricted natural killer (NK) T cells are known to potently secrete T helper (Th) 1 and
Th2 cytokines and to mediate cytolysis, but it is unclear how these contrasting functional …

Natural killer T (NKT) cells are important regulatory lymphocytes that have been shown in
mouse studies, to have a crucial role in promoting immunity to tumours, bacteria and viruses …

Many characteristics distinguish CD1d-reactive natural killer T (NKT) cells that express the
invariant Vα14–Jα18 T-cell receptor (known here as Vα14 i T cells) from conventional T …

A novel lymphocyte lineage, Vα14 natural killer T (NKT) cells, is now well established as
distinct from conventional αβ T cells. Vα14 NKT cells express a single invariant Vα14 …

We studied the function of antitumor T and natural killer T (NKT) cells from the blood and
tumor bed in 23 patients with premalignant gammopathy, nonprogressive myeloma, or …