Mechanisms of diabetes mellitus-induced bone fragility

N Napoli, M Chandran, DD Pierroz… - Nature Reviews …, 2017 - nature.com
The risk of fragility fractures is increased in patients with either type 1 diabetes mellitus
(T1DM) or type 2 diabetes mellitus (T2DM). Although BMD is decreased in T1DM, BMD in …

Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease

E Zaplatic, M Bule, SZA Shah, MS Uddin, K Niaz - Life sciences, 2019 - Elsevier
Quercetin belongs to the flavonoids family, which is present in most of the plants including
fruits, vegetables, green tea and even in red wine having antioxidant activities. It is available …

[HTML][HTML] The Dystrophin Complex: structure, function and implications for therapy

Q Gao, EM McNally - Comprehensive physiology, 2015 - ncbi.nlm.nih.gov
The dystrophin complex stabilizes the plasma membrane of striated muscle cells. Loss of
function mutations in the genes encoding dystrophin, or the associated proteins, triggers …

Muscle-derived fibro-adipogenic progenitor cells for production of cultured bovine adipose tissue

RGJ Dohmen, S Hubalek, J Melke, T Messmer… - npj Science of …, 2022 - nature.com
Cultured meat is an emergent technology with the potential for significant environmental and
animal welfare benefits. Accurate mimicry of traditional meat requires fat tissue; a key …

Impact of diabetes mellitus on bone health

CE Murray, CM Coleman - International journal of molecular sciences, 2019 - mdpi.com
Long-term exposure to a diabetic environment leads to changes in bone metabolism and
impaired bone micro-architecture through a variety of mechanisms on molecular and …

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

A Uezumi, S Fukada, N Yamamoto, S Takeda… - Nature cell …, 2010 - nature.com
Ectopic fat deposition in skeletal muscle is closely associated with several disorders,
however, the origin of these adipocytes is not clear, nor is the mechanism of their formation …

Meta-analysis of diabetes mellitus-associated differences in bone structure assessed by high-resolution peripheral quantitative computed tomography

M Walle, DE Whittier, M Frost, R Müller… - Current osteoporosis …, 2022 - Springer
Abstract Purpose of Review Diabetes mellitus is defined by elevated blood glucose levels
caused by changes in glucose metabolism and, according to its pathogenesis, is classified …

Fetal programming of skeletal muscle development in ruminant animals

M Du, J Tong, J Zhao, KR Underwood… - Journal of animal …, 2010 - academic.oup.com
Enhancing skeletal muscle growth is crucial for animal agriculture because skeletal muscle
provides meat for human consumption. An increasing body of evidence shows that the level …

Advances and challenges in cell biology for cultured meat

B Martins, A Bister, RGJ Dohmen… - Annual review of …, 2024 - annualreviews.org
Cultured meat is an emerging biotechnology that aims to produce meat from animal cell
culture, rather than from the raising and slaughtering of livestock, on environmental and …

The adipose organ

S Cinti - Adipose tissue and adipokines in health and disease, 2007 - Springer
Mammals are provided with an organ that has been neglected by scientists in the past: the
adipose organ. This organ is formed by a series of well-defined depots mainly located at two …