Comparative oncology clinical trials play an important and growing role in cancer research
and drug development efforts. These trials, typically conducted in companion (pet) dogs …

Primary brain tumors are a heterogeneous group of malignancies that originate in cells of
the central nervous system. A variety of models tractable for preclinical studies have been …

The remarkable advances of artificial intelligence (AI) technology are revolutionizing
established approaches to the acquisition, interpretation, and analysis of biomedical …

Naturally occurring canine cancers have remarkable similarities to their human counterparts.
To better understand these similarities, we investigated 671 client-owned dogs from 96 …

Molecular profiling guides precision treatment of breast cancer; however, Asian patients are
underrepresented in publicly available large-scale studies. We established a …

Spontaneous tumors in canines share significant genetic and histological similarities with
human tumors, positioning them as valuable models to guide drug development. However …

Spontaneous canine cancers are valuable but relatively understudied and underutilized
models. To enhance their usage, we reanalyze whole exome and genome sequencing data …

Background Gliomas in dogs remain poorly understood. Objectives To characterize the
clinicopathologic findings, diagnostic imaging features and survival of a large sample of …

Image classification is the act of labeling groups of pixels or voxels of an image based on
some rules. It finds applications in medical image analysis, and satellite image identification …

Pet dogs develop spontaneous cancers at a rate estimated to be five times higher than that
of humans, providing a unique opportunity to study disease biology and evaluate novel …