Cortical-subcortical interactions in goal-directed behavior
Flexibly selecting appropriate actions in response to complex, ever-changing environments
requires both cortical and subcortical regions, which are typically described as participating …
requires both cortical and subcortical regions, which are typically described as participating …
Impairments to visual disengagement in autism spectrum disorder: a review of experimental studies from infancy to adulthood
LAR Sacrey, VL Armstrong, SE Bryson… - Neuroscience & …, 2014 - Elsevier
Impairments in visual disengagement are a current focus of research in autism spectrum
disorders (ASD) and may play a key role in the early expression of social–emotional deficits …
disorders (ASD) and may play a key role in the early expression of social–emotional deficits …
Organization of the inputs and outputs of the mouse superior colliculus
NL Benavidez, MS Bienkowski, M Zhu… - Nature …, 2021 - nature.com
The superior colliculus (SC) receives diverse and robust cortical inputs to drive a range of
cognitive and sensorimotor behaviors. However, it remains unclear how descending cortical …
cognitive and sensorimotor behaviors. However, it remains unclear how descending cortical …
Neural circuits underlying a psychotherapeutic regimen for fear disorders
A psychotherapeutic regimen that uses alternating bilateral sensory stimulation (ABS) has
been used to treat post-traumatic stress disorder. However, the neural basis that underlies …
been used to treat post-traumatic stress disorder. However, the neural basis that underlies …
Superior colliculus bidirectionally modulates choice activity in frontal cortex
Action selection occurs through competition between potential choice options. Neural
correlates of choice competition are observed across frontal cortex and downstream …
correlates of choice competition are observed across frontal cortex and downstream …
Control of orienting movements and locomotion by projection-defined subsets of brainstem V2a neurons
Spatial orientation requires the execution of lateralized movements and a change in the
animal's heading in response to multiple sensory modalities. While much research has …
animal's heading in response to multiple sensory modalities. While much research has …
Cortical and subcortical contributions to short-term memory for orienting movements
Neural activity in frontal cortical areas has been causally linked to short-term memory (STM),
but whether this activity is necessary for forming, maintaining, or reading out STM remains …
but whether this activity is necessary for forming, maintaining, or reading out STM remains …
Selective optogenetic control of Purkinje cells in monkey cerebellum
Purkinje cells of the primate cerebellum play critical but poorly understood roles in the
execution of coordinated, accurate movements. Elucidating these roles has been hampered …
execution of coordinated, accurate movements. Elucidating these roles has been hampered …
Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
J Essig, JB Hunt, G Felsen - Communications Biology, 2021 - nature.com
Decision making is a cognitive process that mediates behaviors critical for survival.
Choosing spatial targets is an experimentally-tractable form of decision making that …
Choosing spatial targets is an experimentally-tractable form of decision making that …
Functional organisation of the mouse superior colliculus
The superior colliculus (SC) is a highly conserved area of the mammalian midbrain that is
widely implicated in the organisation and control of behaviour. SC receives input from a …
widely implicated in the organisation and control of behaviour. SC receives input from a …