Strategies for Organ‐Targeted mRNA Delivery by Lipid Nanoparticles

H Liao, J Liao, L Zeng, X Cao, H Fan… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Messenger RNA (mRNA) technology has rapidly evolved, significantly impacting various
therapeutic applications, including vaccines, protein replacement, and gene editing. Lipid …

An innovative approach for parkinson's disease diagnosis using CNN, NCA, and SVM

Y Dogan - Neural Computing and Applications, 2024 - Springer
Parkinson's disease (PD) is a prevalent neurodegenerative disorder affecting millions of
people globally, with substantial health risks and economic burdens. This study aims to …

Harnessing Graphdiyne for Selective Cu2+ Detection: A Promising Tool for Parkinson's Disease Diagnostics and Pathogenesis

J Jiang, X Wang, Y Bao, F Shen, G Wang, K Li… - ACS …, 2024 - ACS Publications
Cu2+ accelerates the viral-like propagation of α-synuclein fibrils and plays a key role in the
pathogenesis of Parkinson's disease (PD). Therefore, the accurate detection of Cu2+ is …

Serum metabolomic profiling for predicting therapeutic response and toxicity in breast cancer neoadjuvant chemotherapy: a retrospective longitudinal study

Z Fang, G Ren, S Ke, Q Xu, Y Chen, X Shi, C Guo… - Breast Cancer …, 2025 - Springer
Background Neoadjuvant chemotherapy (NACT) is the standard-of-care treatment for
patients with locally advanced breast cancer (LABC), providing crucial benefits in tumor …

An activated fluorescent probe to monitor NO fluctuation in Parkinson's disease

T Liu, X Han, X Sun, W Zhang, K Gao, R Min… - Chinese Chemical …, 2024 - Elsevier
The imbalance of nitric oxide (NO) homeostasis in the brain is closely related to the
occurrence of Parkinson's disease (PD). Therefore, revealing the fluctuation of NO in brain is …

Discovery of plasma biomarkers for Parkinson's disease diagnoses based on metabolomics and lipidomics

X Wang, B Wang, F Ji, J Yan, J Fang, D Zhang… - Chinese Chemical …, 2024 - Elsevier
Parkinson's disease (PD) is an aging-associated neurodegenerative movement disorder
with increasing morbidity and mortality rates. The current gold standard for diagnosing PD is …

A novel hybrid CNN-KNN ensemble voting classifier for Parkinson's disease prediction from hand sketching images

S Saleh, A Ouhmida, B Cherradi, M Al-Sarem… - Multimedia Tools and …, 2024 - Springer
Parkinson's disease is a progressive neurodegenerative disorder that causes significant
physical disabilities and reduces the quality of life. This disease is caused by the loss of …

Unveiling and swift diagnosing chronic wound healing with artificial intelligence assistance

J Deng, G Shi, Z Ye, Q Xiao, X Zhang, L Ren… - Chinese Chemical …, 2024 - Elsevier
Histopathological analysis of chronic wounds is crucial for clinicians to accurately assess
wound healing progress and detect potential malignancy. However, traditional pathological …

[HTML][HTML] AIoT-based embedded systems optimization using feature selection for Parkinson's disease diagnosis through speech disorders

S Saleh, Z Alouani, O Daanouni, S Hamida… - Intelligence-Based …, 2024 - Elsevier
This study aims to build a pre-diagnosis tool for predicting Parkinson's disease based on a
speech disorder which appears as a symptom in approximately 90% of people with this …