Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

The calibrated application of limited-duration, cyclic, moderately intense hypoxia-
reoxygenation increases cardiac resistance to ischemia-reperfusion stress. These …

The COVID-19 pandemic has led to several pioneering scientific discoveries resulting in no
effective solutions with the exception of vaccination. Moderate exercise is a significant non …

The ability to sense and respond to oxygen deprivation is required for survival; thus,
understanding the mechanisms by which changes in oxygen are linked to cell viability and …

It has been documented that reactive oxygen species (ROS) contribute to oxidative stress,
leading to diseases such as ischemic heart disease. Recently, increasing evidence has …

This review deals with the capability of the heart to adapt to chronic hypoxia in animals
exposed to either natural or simulated high altitude. From the broad spectrum of related …

The aim was to determine whether increased oxidative stress during the adaptation to
chronic intermittent hypoxia (CIH) plays a role in the induction of improved cardiac ischemic …

Obstructive sleep apnea is associated with increased risk for cardiovascular diseases. As
obstructive sleep apnea is characterized by episodic cycles of hypoxia and normoxia during …

Ischemia and reperfusion (I/R) cause a reduction in arterial blood supply to tissues, followed
by the restoration of perfusion and consequent reoxygenation. The reestablishment of blood …

The role of mitochondrial permeability transition pore (MPTP) in the mechanism of
intermittent high altitude (IHA) hypoxic adaptation is not understood. Therefore, we study …