Improving the adherence to antiretroviral therapy, a difficult but essential task for a successful HIV treatment—clinical points of view and practical considerations

SA Iacob, DG Iacob, G Jugulete - Frontiers in pharmacology, 2017 - frontiersin.org
HIV infection is responsible for one the most devastating human pandemics. The advent of
antiretroviral therapy has changed the course of the pandemic and saved millions of lives …

Retention in HIV care during pregnancy and the postpartum period in the option B+ era: systematic review and meta-analysis of studies in Africa

BA Knettel, C Cichowitz, JS Ngocho… - JAIDS Journal of …, 2018 - journals.lww.com
Background: Under Option B+ guidelines for prevention of mother-to-child transmission of
HIV, pregnant and breastfeeding women initiate antiretroviral therapy for lifelong use. The …

The Joint United Nations Programme on HIV/AIDS 95–95–95 targets: worldwide clinical and cost benefits of generic manufacture

K Heath, J Levi, A Hill - Aids, 2021 - journals.lww.com
Background: The Joint United Nations Programme on HIV/AIDS aims for HIV testing,
treatment and viral suppression rates to be 95%--95%--95% by 2025. Patented drug prices …

Effect of a differentiated service delivery model on virological failure in adolescents with HIV in Zimbabwe (Zvandiri): a cluster-randomised controlled trial

W Mavhu, N Willis, J Mufuka, S Bernays… - The Lancet Global …, 2020 - thelancet.com
Background Adolescents living with HIV face challenges to their wellbeing and antiretroviral
therapy adherence and have poor treatment outcomes. We aimed to evaluate a peer-led …

Recent interventions to improve retention in HIV care and adherence to antiretroviral treatment among adolescents and youth: a systematic review

M Casale, A Carlqvist, L Cluver - AIDS patient care and STDs, 2019 - liebertpub.com
Adolescents represent a growing proportion of people living with HIV worldwide and the
highest risk population group for treatment attrition and AIDS-related mortality. There is an …

Psychosocial support interventions for improved adherence and retention in ART care for young people living with HIV (10–24 years): a scoping review

EF Okonji, FC Mukumbang, Z Orth… - BMC public health, 2020 - Springer
Background Mental health disorders such as high levels of anxiety, isolation, depression
and suicide ideation reported among young people living with HIV (10–24 years; YPLHIV) …

Adherence clubs and decentralized medication delivery to support patient retention and sustained viral suppression in care: Results from a cluster-randomized …

MP Fox, S Pascoe, AN Huber, J Murphy… - PLoS …, 2019 - journals.plos.org
Background Differentiated antiretroviral therapy (ART) delivery models, in which patients are
provided with care relevant to their current status (eg, newly initiating, stable on treatment, or …

Adherence measurements in HIV: new advancements in pharmacologic methods and real-time monitoring

JR Castillo-Mancilla, JE Haberer - Current Hiv/aids Reports, 2018 - Springer
Abstract Purpose of Review In this review, we present new developments in antiretroviral
adherence, focusing on pharmacological measures and real-time adherence monitoring. In …

A review of differentiated service delivery for HIV treatment: effectiveness, mechanisms, targeting, and scale

M Roy, C Bolton Moore, I Sikazwe… - Current HIV/AIDS Reports, 2019 - Springer
Abstract Purpose of Review Differentiated service delivery (DSD) models were initially
developed as a means to combat suboptimal long-term retention in HIV care, and to better …

Global implementation of PrEP for HIV prevention: setting expectations for impact

MN Pyra, JE Haberer, N Hasen, J Reed… - African Journal of …, 2019 - journals.lww.com
Introduction: Questions remain whether HIV pre-exposure prophylaxis (PrEP) can be
translated into a successful public health intervention, leading to a decrease in population …