Autophagy is a process of self-degradation that plays an important role in removing
damaged proteins, organelles or cellular fragments from the cell. Under stressful conditions …

Cancer therapy is one of the most important challenges of modern medical and chemical
sciences. Among the many methods of combating cancer, chemotherapy plays a special …

The discovery of cytotoxic drugs is focused on designing a compound structure that directly
affects cancer cells without an impact on normal cells. The mechanism of anticancer activity …

Two new Schiff base ligands (TE and TF) were prepared from conjugation of testosterone
with 4-(4-ethylphenyl)-3-thiosemicarbazide and 4-(4-fluorophenyl)-3-thiosemicarbazide …

Many studies have shown that naturally occurring compounds may support prevention and
treatment of various diseases, including cancer. Pharmacological investigations revealed a …

The aim of the present study was to examine the multi‑targeted potential of a monoclonal
antibody against mucin‑1 (MUC1) and novel octahydropyrazin [2, 1‑a: 5, 4‑a'] diisoquinoline …

Objective The aim of the current study was to examine the anticancer activity and the
detailed mechanism of novel diisoquinoline derivatives in human gastric cancer cells (AGS) …

Background: The aim of the study was to examine the molecular mechanism of the
anticancer action of a monoclonal antibody against MUC1 and a diisoquinoline derivative …

Background Caspases play important roles in apoptosis and inflammation. ICT's FLICA
assay kits are used by researchers seeking to quantitate apoptosis via caspase activity in …

The side effects of cisplatin such as toxicities are mainly due to the lack of selectivity of this
chemotherapeutic agent. In order to increase the selectivity of an anticancer agent, hormone …