A review on recent approaches on molecular docking studies of novel compounds targeting acetylcholinesterase in Alzheimer disease
SC Peitzika, E Pontiki - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
Metal complexes of hydrazone–oxime derivative as promising in vitro antimicrobial agents against some fungal and bacterial strains
EA Hassan, MM Ebrahium… - Applied Organometallic …, 2022 - Wiley Online Library
In this study, Cu2+, Co2+, Ni2+, Mn2+, Zn2+, Fe3+, VO2+, and UO22+ complexes derived
from a NNO tridentate chelating hydrazone–oxime, namely, N′‐((2E, 3Z)‐3‐(hydroxyimino) …
from a NNO tridentate chelating hydrazone–oxime, namely, N′‐((2E, 3Z)‐3‐(hydroxyimino) …
Synthesis of isoniazid analogs with promising antituberculosis activity and bioavailability: biological evaluation and computational studies
R Gavadia, J Rasgania, MV Basil, V Chauhan… - Journal of Molecular …, 2023 - Elsevier
A series of aliphatic isoniazid carbo (x/thio) amides has been synthesized by a facile one-pot
green method in aqueous media by harnessing microwave irradiations. In vitro …
green method in aqueous media by harnessing microwave irradiations. In vitro …
Exploring etofenamate hydrazide-hydrazone/copper (II) complexes: Synthesis, anticancer activity, carbonic anhydrase IX inhibition and docking studies
Hydrazide-hydrazone derivatives have garnered significant interest from researchers
globally due to their wide range of biological activities, including antiviral, anticancer, and …
globally due to their wide range of biological activities, including antiviral, anticancer, and …
Glycerol based carbon sulfonic acid catalyzed synthesis, in silico studies and in vitro biological evaluation of isonicotinohydrazide derivatives as potent antimicrobial …
The present pathway involves synthesis of isonicotinohydrazide derivatives using isoniazid
and diversely substituted aldehydes in the presence of EtOH and catalytic amount of …
and diversely substituted aldehydes in the presence of EtOH and catalytic amount of …
Tridentate N-Acylhydrazones as Moderate Ligands for the Potential Management of Cognitive Decline Associated With Metal-Enhanced Neuroaggregopathies
DS Cukierman, NA Rey - Frontiers in Neurology, 2022 - frontiersin.org
The relevance of some endogenous metals, such as the redox-active copper and iron, and
the putative neuromodulator zinc, to neurodegeneration is quite well documented in the …
the putative neuromodulator zinc, to neurodegeneration is quite well documented in the …
Microwave-assisted synthesis of Schiff bases of isoniazid and evaluation of their anti-proliferative and antibacterial activities
Three new Schiff bases of isoniazid were synthesized using microwave-assisted synthesis
and conventional condensation with aromatic aldehydes. Synthesized compounds were …
and conventional condensation with aromatic aldehydes. Synthesized compounds were …
Exploration of potent multi-target-directed-ligands as anti-alzheimer's disease agents: A moiety based review
Dementia is a chronic neurodegenerative disease, and a maximum number of the cases are
directly related to Alzheimer's disease. More than 4 million people are living with Alzheimer's …
directly related to Alzheimer's disease. More than 4 million people are living with Alzheimer's …
4-Hydroxybenzoic Acid-Based Hydrazide–Hydrazones as Potent Growth Inhibition Agents of Laccase-Producing Phytopathogenic Fungi That Are Useful in the …
The research on new compounds against plant pathogens is still socially and economically
important. It results from the increasing resistance of pests to plant protection products and …
important. It results from the increasing resistance of pests to plant protection products and …
Synthesis of highly potent anti-inflammatory compounds (ROS inhibitors) from isonicotinic acid
In search of anti-inflammatory compounds, novel scaffolds containing isonicotinoyl motif
were synthesized via an efficient strategy. The compounds were screened for their in vitro …
were synthesized via an efficient strategy. The compounds were screened for their in vitro …