Integrins are heterodimeric cell surface receptors ensuring the mechanical connection
between cells and the extracellular matrix. In addition to the anchorage of cells to the …

The nongenomic actions of thyroid hormone begin at receptors in the plasma membrane,
mitochondria or cytoplasm. These receptors can share structural homologies with nuclear …

The interdependence between thyroid hormones (THs), namely, thyroxine and
triiodothyronine, and immune system is nowadays well-recognized, although not yet fully …

Thyroid hormones take major part in normal growth, development and metabolism. Over a
century of research has supported a relationship between thyroid hormones and the …

The extracellular domain of plasma membrane integrin αvβ3 contains a cell surface receptor
for thyroid hormone analogues. The receptor is largely expressed and activated in tumor …

Integrin αvβ3, a cell surface receptor, participates in signaling transduction pathways in
cancer cell proliferation and metastasis. Several ligands bind to integrin αvβ3 to regulate …

The genomic actions of thyroid hormone and steroids depend upon primary interactions of
the hormones with their specific nuclear receptor proteins. Formation of nuclear co-activator …

Metastasis to bone is a frequent occurrence in patients with breast and prostate cancers and
inevitably threatens the patient's quality of life and survival. Identification of cancer‐derived …

Background Uptake of coronaviruses by target cells involves binding of the virus by cell
ectoenzymes. For the etiologic agent of COVID-19 (SARS-CoV-2), a receptor has been …

Integrin αvβ3 is generously expressed by cancer cells and rapidly dividing endothelial cells.
The principal ligands of the integrin are extracellular matrix proteins, but we have described …