Metabolic messengers: tumour necrosis factor

JK Sethi, GS Hotamisligil - Nature metabolism, 2021 - nature.com
Tumour necrosis factor (TNF) is a classical, pleiotropic pro-inflammatory cytokine. It is also
the first 'adipokine'described to be produced from adipose tissue, regulated in obesity and …

Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication

JB Funcke, PE Scherer - Journal of lipid research, 2019 - ASBMB
The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

Fructose induces visceral adipose tissue inflammation and insulin resistance even without development of obesity in adult female but not in male rats

S Kovačević, J Brkljačić, D Vojnović Milutinović… - Frontiers in …, 2021 - frontiersin.org
Introduction: Obesity and related metabolic disturbances are frequently related to modern
lifestyle and are characterized by excessive fructose intake. Visceral adipose tissue (VAT) …

Tamarind trypsin inhibitor in chitosan–whey protein nanoparticles reduces fasting blood glucose levels without compromising insulinemia: A preclinical study

LLR Matias, ROA Costa, TS Passos, JLC Queiroz… - Nutrients, 2019 - mdpi.com
In vivo studies show the benefits of the trypsin inhibitor isolated from tamarind
(Tamarindusindica L.)(TTI) seeds in satiety and obesity. In the present study, TTI …

Adipocytes and intestinal epithelium dysfunctions linking obesity to inflammation induced by high glycemic index pellet-diet in Wistar rats

ABS Luz, JB dos Santos Figueredo… - Bioscience …, 2018 - portlandpress.com
We investigated the inflammatory effect of a pellet-diet with high glycemic index and load
(HGLI) on the histological organization of adipocytes, intestinal epithelium, and fat in liver …

[HTML][HTML] Safety and bioactive potential of nanoparticles containing Cantaloupe melon (Cucumis melo L.) carotenoids in an experimental model of chronic inflammation

I Medeiros, GLR de Oliveira, JLC de Queiroz… - Biotechnology …, 2020 - Elsevier
The safety and bioactive potential of crude carotenoid extract from Cantaloupe melon
nanoencapsulated in porcine gelatin (EPG) were evaluated in a chronic inflammatory …

Role of adipose tissue inflammation in fat pad loss induced by fasting in lean and mildly obese mice

DR Lacerda, KA Costa, ALM Silveira… - The Journal of …, 2019 - Elsevier
Inflammation induced by obesity contributes to insulin resistance and atherosclerosis.
Indeed, high levels of proinflammatory cytokines trigger chronic low-grade inflammation and …

Effect of high-refined carbohydrate diet on intestinal integrity

KA Costa, MC de Oliveira, LM de Souza Cordeiro… - Nutrition, 2023 - Elsevier
Objectives One of the leading causes of obesity is the consumption of excess nutrients.
Obesity is characterized by adipose tissue expansion, chronic low-grade inflammation, and …

Interactions between weight loss and plasma neurodegenerative markers for determining cognitive decline among community-dwelling older adults

KV Giudici, S Guyonnet, JE Morley… - The Journals of …, 2022 - academic.oup.com
This study aimed to investigate the interaction between weight loss (WL) and plasma
amyloid-β 42/40 (Aβ 42/40), neurofilament light chain (NfL), progranulin, and their …

Comparison of the value of adipose tissues in abdomen and lumbar vertebra for predicting disease activity in Crohn's disease: A preliminary study based on CSE-MRI

S Wang, G Tang, S Liu, Y Tu, R Ji, R Tang… - Magnetic Resonance …, 2024 - Elsevier
Background To compare the value of adipose tissues in abdomen and lumbar vertebra for
predicting Crohn's disease (CD) activity based on chemical shift encoded magnetic …