Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates
pathological remodeling processes that involve inflammation and fibrosis in cardiovascular …

It is now becoming apparent that dynamic changes occur within the interstitium that directly
contribute to adverse myocardial remodeling following myocardial infarction (MI), with …

Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes responsible for
myocardial extracellular protein degradation. Several MMP species identified within the …

Background: Evaluation of patients who present to the hospital with a complaint of chest
pain or other signs or symptoms suggestive of acute coronary syndrome (ACS) is time …

Background—Alterations in the balance of matrix metalloproteinases (MMPs) and their
specific tissue inhibitors (TIMPs) are involved in left ventricular (LV) remodeling. Whether …

Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …

The post-myocardial infarction wound repair process involves temporarily overlapping
phases that include inflammation, formation of granulation tissue, scar formation, and overall …

Objectives: We sought to assess the distribution of collagen deposits and collagen
degradation in hypertensive patients with either systolic heart failure (SHF) or diastolic heart …

Background—A potential mechanism for left ventricular (LV) remodeling after myocardial
infarction (MI) is activation of the matrix metalloproteinases (MMPs). This study examined the …

Objectives: We studied the role of matrix metalloproteinases (MMPs) and their tissue
inhibitors (TIMPs) in fibrosis formation in the transition from hypertrophy to heart failure (HF) …