Quantitative approaches to guide epilepsy surgery from intracranial EEG

JM Bernabei, A Li, AY Revell, RJ Smith… - Brain, 2023 - academic.oup.com
Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

Differential cortical network engagement during states of un/consciousness in humans

R Zelmann, AC Paulk, F Tian, GAB Villegas, JD Peralta… - Neuron, 2023 - cell.com
What happens in the human brain when we are unconscious? Despite substantial work, we
are still unsure which brain regions are involved and how they are impacted when …

Network connectivity predicts effectiveness of responsive neurostimulation in focal epilepsy

JM Fan, AT Lee, K Kudo, KG Ranasinghe… - Brain …, 2022 - academic.oup.com
Responsive neurostimulation is a promising treatment for drug-resistant focal epilepsy;
however, clinical outcomes are highly variable across individuals. The therapeutic …

[HTML][HTML] Imaging and SEEG Functional Networks to Guide Epilepsy Surgery

DJ Doss, GW Johnson… - Neurosurgery Clinics of …, 2023 - pmc.ncbi.nlm.nih.gov
Imaging and SEEG Functional Networks to Guide Epilepsy Surgery - PMC Skip to main content
Here's how you know Official websites use .gov A .gov website belongs to an official government …

Cortico-cortical evoked potentials in response to varying stimulation intensity improves seizure localization

MA Hays, RJ Smith, Y Wang, C Coogan… - Clinical …, 2023 - Elsevier
Objective As single pulse electrical stimulation (SPES) is increasingly utilized to help
localize the seizure onset zone (SOZ), it is important to understand how stimulation intensity …

Source-sink connectivity: A novel interictal EEG marker for seizure localization

KM Gunnarsdottir, A Li, RJ Smith, JY Kang… - Brain, 2022 - academic.oup.com
Over 15 million epilepsy patients worldwide have drug-resistant epilepsy. Successful
surgery is a standard of care treatment but can only be achieved through complete resection …

Stimulation to probe, excite, and inhibit the epileptic brain

B Frauscher, F Bartolomei, MO Baud, RJ Smith… - …, 2023 - Wiley Online Library
Direct cortical stimulation has been applied in epilepsy for nearly a century and has
experienced a renaissance, given unprecedented opportunities to probe, excite, and inhibit …

Stimulating native seizures with neural resonance: a new approach to localize the seizure onset zone

RJ Smith, MA Hays, G Kamali, C Coogan, NE Crone… - Brain, 2022 - academic.oup.com
Successful outcomes in epilepsy surgery rely on the accurate localization of the seizure
onset zone. Localizing the seizure onset zone is often a costly and time-consuming process …

Localizing seizure onset zone by a cortico-cortical evoked potentials-based machine learning approach in focal epilepsy

B Yang, B Zhao, C Li, J Mo, Z Guo, Z Li, Y Yao… - Clinical …, 2024 - Elsevier
Objective We aimed to develop a new approach for identifying the localization of the seizure
onset zone (SOZ) based on corticocortical evoked potentials (CCEPs) and to compare the …

Diagnosing epilepsy with normal interictal EEG using dynamic network models

P Myers, K Gunnarsdottir, A Li, V Razskazovskiy… - medRxiv, 2023 - medrxiv.org
Objective While scalp EEG is important for diagnosing epilepsy, a single routine EEG is
limited in its diagnostic value. Only a small percentage of routine EEGs show interictal …