Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease

G Fancellu, K Chand, D Tomás… - Journal of enzyme …, 2020 - Taylor & Francis
Pursuing the widespread interest on multi-target drugs to combat Alzheimer´ s disease (AD),
a new series of hybrids was designed and developed based on the repositioning of the well …

Correlations of synthetic, spectroscopic, structural, and speciation studies in the biologically relevant cobalt (II)− citrate system: the tale of the first aqueous dinuclear …

N Kotsakis, CP Raptopoulou, V Tangoulis… - Inorganic …, 2003 - ACS Publications
Synthetic efforts targeting soluble species of Co (II) with the low molecular mass
physiological ligand citric acid led to the isolation of the first dinuclear complex [Co2 …

Evaluation of the binding of oxovanadium (IV) to human serum albumin

I Correia, T Jakusch, E Cobbinna, S Mehtab… - Dalton …, 2012 - pubs.rsc.org
The understanding of the biotransformations of insulin mimetic vanadium complexes in
human blood and its transport to target cells is an essential issue in the development of …

Resveratrol–maltol and resveratrol–thiophene hybrids as cholinesterase inhibitors and antioxidants: synthesis, biometal chelating capability and crystal structure

M Mlakić, L Fodor, I Odak, O Horváth, MJ Lovrić… - Molecules, 2022 - mdpi.com
New resveratrol–thiophene and resveratrol–maltol hybrids were synthesized as
cholinesterase inhibitors and antioxidants. As with photostability experiments, biological …

Ternary complex formation between VO (IV)–picolinic acid or VO (IV)–6-methylpicolinic acid and small blood serum bioligands

E Kiss, E Garribba, G Micera, T Kiss… - Journal of Inorganic …, 2000 - Elsevier
In order to assess the role of the low molecular mass bioligands of blood serum in vanadium
binding, a study was made of the interactions of the complexes formed in the VO (IV) …

A two-dimensional (magnetic field and concentration) electron paramagnetic resonance method for analysis of multispecies complex equilibrium systems. Information …

A Rockenbauer, T Szabó-Plánka… - Journal of the …, 2001 - ACS Publications
A two-dimensional simulation method has been developed for the interpretation of electron
paramagnetic resonance (EPR) spectra consisting of a multitude of strongly overlapping …

Multinuclear complex formation between Ca (II) and gluconate ions in hyperalkaline solutions

A Pallagi, ÉG Bajnóczi, SE Canton, T Bolin… - … science & technology, 2014 - ACS Publications
Alkaline solutions containing polyhydroxy carboxylates and Ca (II) are typical in
cementitious radioactive waste repositories. Gluconate (Gluc–) is a structural and functional …

AsIII Selectively Induces a Disorder-to-Order Transition in the Metalloid Binding Region of the AfArsR Protein

A Tóth, K Sajdik, B Gyurcsik, ZH Nafaee… - Journal of the …, 2024 - ACS Publications
Arsenic is highly toxic and a significant threat to human health, but certain bacteria have
developed defense mechanisms initiated by AsIII binding to AsIII-sensing proteins of the …

Characterization of chemical speciation of titanyl sulfate solutions for production of titanium dioxide precipitates

I Szilágyi, E Königsberger, PM May - Inorganic chemistry, 2009 - ACS Publications
Ion association in concentrated aqueous solutions of titanyl sulfate in sulfuric acid has been
investigated at 25° C by Raman spectroscopy under conditions like those used in the …

Zn II and Hg II binding to a designed peptide that accommodates different coordination geometries

D Szunyogh, B Gyurcsik, FH Larsen, M Stachura… - Dalton …, 2015 - pubs.rsc.org
Designed metal ion binding peptides offer a variety of applications in both basic science as
model systems of more complex metalloproteins, and in biotechnology, eg in bioremediation …