[HTML][HTML] Hyaluronic acid and chondroitin sulfate (meth) acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation

CCL Schuurmans, M Mihajlovic, C Hiemstra, K Ito… - Biomaterials, 2021 - Elsevier
Hydrogels based on photocrosslinkable Hyaluronic Acid Methacrylate (HAMA) and
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …

[HTML][HTML] How to plumb a pisces: understanding vascular development and disease using zebrafish embryos

BM Hogan, S Schulte-Merker - Developmental cell, 2017 - cell.com
Our vasculature plays diverse and critical roles in homeostasis and disease. In recent
decades, the use of zebrafish has driven our understanding of vascular development into …

Stem cell membrane‐coated microribbon scaffolds induce regenerative innate and adaptive immune responses in a critical‐size cranial bone defect model

N Su, C Villicana, D Barati, P Freeman… - Advanced …, 2023 - Wiley Online Library
Naturally‐derived cell membranes have shown great promise in functionalizing
nanoparticles to enhance biointerfacing functions for drug delivery applications. However, its …

The extracellular matrix integrates mitochondrial homeostasis

H Zhang, CK Tsui, G Garcia, LK Joe, H Wu, A Maruichi… - Cell, 2024 - cell.com
Cellular homeostasis is intricately influenced by stimuli from the microenvironment, including
signaling molecules, metabolites, and pathogens. Functioning as a signaling hub within the …

Cell energy metabolism and hyaluronan synthesis

I Caon, A Parnigoni, M Viola… - … of Histochemistry & …, 2021 - journals.sagepub.com
Hyaluronan (HA) is a linear glycosaminoglycan (GAG) of extracellular matrix (ECM)
synthesized by three hyaluronan synthases (HASes) at the plasma membrane using uridine …

Optical microscopy and the extracellular matrix structure: a review

JJA Poole, LB Mostaço-Guidolin - Cells, 2021 - mdpi.com
Biological tissues are not uniquely composed of cells. A substantial part of their volume is
extracellular space, which is primarily filled by an intricate network of macromolecules …

[HTML][HTML] The hyaluronidase, TMEM2, promotes ER homeostasis and longevity independent of the UPRER

RT Schinzel, R Higuchi-Sanabria, O Shalem… - Cell, 2019 - cell.com
Cells have evolved complex mechanisms to maintain protein homeostasis, such as the UPR
ER, which are strongly associated with several diseases and the aging process. We …

Basic Biology of Extracellular Matrix in the Cardiovascular System, Part 1/4: JACC Focus Seminar

G del Monte-Nieto, JW Fischer, DJ Gorski… - Journal of the American …, 2020 - jacc.org
The extracellular matrix (ECM) is the noncellular component of tissues in the cardiovascular
system and other organs throughout the body. It is formed of filamentous proteins …

tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis

AM Savage, S Kurusamy, Y Chen, Z Jiang… - Nature …, 2019 - nature.com
Angiogenesis requires co-ordination of multiple signalling inputs to regulate the behaviour
of endothelial cells (ECs) as they form vascular networks. Vascular endothelial growth factor …

Insights into the source, mechanism and biotechnological applications of hyaluronidases

YS Zhang, JS Gong, ZY Yao, JY Jiang, C Su, H Li… - Biotechnology …, 2022 - Elsevier
It has long been found that hyaluronidases exist in a variety of organisms, playing their roles
in various biological processes including infection, envenomation and metabolic regulation …