DNA lesion bypass and the stochastic dynamics of transcription-coupled repair

MD Nicholson, CJ Anderson… - Proceedings of the …, 2024 - National Acad Sciences
DNA base damage is a major source of oncogenic mutations and disruption to gene
expression. The stalling of RNA polymerase II (RNAP) at sites of DNA damage and the …

The Surprising Diversity of UV‐Induced Mutations

MF Laughery, HE Wilson, A Sewell… - Advanced …, 2024 - Wiley Online Library
Ultraviolet (UV) light is the most pervasive environmental mutagen and the primary cause of
skin cancer. Genome sequencing of melanomas and other skin cancers has revealed that …