Primary ovarian insufficiency (POI) is a rare but important cause of ovarian hormone
deficiency and infertility in women. In addition to causing infertility, POI is associated with …

Androgens are an important and diverse group of steroid hormone molecular species. They
play varied functional roles, such as the control of metabolic energy fate and partition, the …

Abstract Objective To update the “Evaluation and Treatment of Hirsutism in Premenopausal
Women: An Endocrine Society Clinical Practice Guideline,” published by the Endocrine …

Objective: To update practice guidelines for the therapeutic use of androgens in women.
Participants: A Task Force appointed by the Endocrine Society, American Congress of …

BACKGROUND Combined oral contraceptives (COCs) reduce levels of androgen,
especially testosterone (T), by inhibiting ovarian and adrenal androgen synthesis and by …

Objective: The objective of the study was to evaluate the current state of clinical assays for
total and free testosterone. Participants: The five participants were appointed by the Council …

Objective: There is increasing laboratory evidence for a neuroprotective effect of estrogen;
however, the clinical and epidemiologic evidence remains limited and conflicting. We …

Over a decade ago, we proposed a “unitary” model for the pathogenesis of osteoporosis that
identified estrogen deficiency as the predominant cause of both the early, accelerated, and …

Objective: Our objective was to develop clinical practice guidelines for the evaluation and
treatment of hirsutism in premenopausal women. Participants: The Task Force was …

Background The efficacy and safety of testosterone treatment for hypoactive sexual desire
disorder in postmenopausal women not receiving estrogen therapy are unknown. Methods …