Prospection of recent chitosan biomedical trends: Evidence from patent analysis (2009–2020)

M Kurakula - International Journal of Biological Macromolecules, 2020 - Elsevier
Improved accuracy is one of the vital innovations in designing biopolymer-based products
that are gaining momentum in diverse biomedicine arenas. The innovative devices were …

Intriguing of pharmaceutical product development processes with the help of artificial intelligence and deep/machine learning or artificial neural network

N Jariwala, CL Putta, K Gatade, M Umarji… - Journal of Drug Delivery …, 2023 - Elsevier
The objectives of current review are (1) to provide a historical overview of artificial
intelligence and deep/machine learning (AI & D/ML) or Artificial Neural Network (ANN)(2) to …

Optimization of process parameters for fabrication of electrospun nanofibers containing neomycin sulfate and Malva sylvestris extract for a better diabetic wound …

M Monirul Islam, V HR, P Durga Bhavani… - Drug Delivery, 2022 - Taylor & Francis
Diabetes mellitus is one of the most concerning conditions, and its chronic consequences
are almost always accompanied by infection, oxidative stress, and inflammation. Reducing …

In situ gel loaded with chitosan-coated simvastatin nanoparticles: Promising delivery for effective anti-proliferative activity against tongue carcinoma

M Kurakula, NR Naveen - Marine Drugs, 2020 - mdpi.com
The goal of this study is to develop optimized chitosan-coated Simvastatin (SIM)
nanoparticles (NPs) loaded in an in situ gel (ISG) formulation via a face-centered central …

Preparation and characterization of 3D bioprinted gelatin methacrylate hydrogel incorporated with curcumin loaded chitosan nanoparticles for in vivo wound healing …

K Khoshmaram, F Yazdian, Z Pazhouhnia… - Biomaterials …, 2024 - Elsevier
This study developed a biomimetic composite bioink consisting of gelatin methacrylate
(GelMA)/chitosan nanoparticles (CSNPs) for extrusion-based 3D bioprinting. Additionally …

Design and development of neomycin sulfate gel loaded with solid lipid nanoparticles for buccal mucosal wound healing

KM Hosny, NR Naveen, M Kurakula, AM Sindi… - Gels, 2022 - mdpi.com
Drug administration to the wound site is a potential method for wound healing. The drug
retention duration should be extended, and drug permeability through the buccal mucosal …

Preparation, optimization and evaluation of chitosan-based avanafil nanocomplex utilizing antioxidants for enhanced neuroprotective effect on PC12 cells

M Kurakula, R Naveen N, B Patel, R Manne, DB Patel - Gels, 2021 - mdpi.com
(1) Introduction: in recent decades, interdisciplinary research on the utilization of natural
products as “active moiety carriers” was focused on due to their superior safety profile …

Compression-coated pulsatile chronomodulated therapeutic system: QbD assisted optimization

HM Aldawsari, NR Naveen, NA Alhakamy… - Drug Delivery, 2022 - Taylor & Francis
Pulsatile drug delivery systems have drawn attention in contemporary research for
designing chronotherapeutic systems. The current work aims to design pulsatile ketorolac …

QbD supported optimization of the alginate-chitosan nanoparticles of simvastatin in enhancing the anti-proliferative activity against tongue carcinoma

WY Rizg, NR Naveen, M Kurakula, HA Bukhary… - Gels, 2022 - mdpi.com
The goal of the current study is to develop a chitosan alginate nanoparticle system
encapsulating the model drug, simvastatin (SIM-CA-NP) using a novel polyelectrolytic …

Response surface methodology (RSM) powered formulation development, optimization and evaluation of thiolated based mucoadhesive nanocrystals for local …

RB Bakhaidar, NR Naveen, P Basim, SS Murshid… - Polymers, 2022 - mdpi.com
In oral administration systems, mucoadhesive polymers are crucial for drug localization and
target-specific activities. The current work focuses on the application of thiolated xanthan …