Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

A mosquito needs to ingest at least one male and one female gametocyte to become
infected with malaria. The sex of Plasmodium falciparum gametocytes can be determined …

Background Pyronaridine-artesunate (PA) is indicated for the treatment of acute
uncomplicated Plasmodium falciparum and Plasmodium vivax malaria. Methods Individual …

While significant advances have been made in understanding Plasmodium falciparum
gametocyte biology and its relationship with malaria parasite transmission, the gametocyte …

While significant advances have been made in the prevention and treatment of malaria in
recent years, these successes continue to fall short of the World Health Organization (WHO) …

Background. Artemisinin-based combination therapies (ACTs) have been widely adopted as
first-line agents to treat uncomplicated falciparum malaria due to their activity against …

Background Amodiaquine is frequently used as a partner drug in combination therapy or in
some setting as monotherapy, but little is known about its effects on gametocyte production …

The sex ratios of Plasmodium falciparum gametocytes, defined as the proportion of
gametocytes in peripheral blood that were male, were evaluated in 1609 children with acute …

Background Considering the distinct biological characteristics of Plasmodium species is
crucial for control and elimination efforts, in particular when facing the spread of drug …

The gametocyte sex ratio (proportion of gametocytes that are male) of Plasmodium
falciparum may influence transmission. The distribution of P. falciparum sex ratios, the extent …