Noninvasive plaque imaging to accelerate coronary artery disease drug development
Coronary artery disease (CAD) remains the leading cause of adult mortality globally.
Targeting known modifiable risk factors has had substantial benefit, but there remains a …
Targeting known modifiable risk factors has had substantial benefit, but there remains a …
Positron emission tomography in the diagnosis and follow-up of transthyretin amyloid cardiomyopathy patients: a systematic review
HSA Tingen, A Tubben, JH Van'T Oever… - European journal of …, 2023 - Springer
Purpose Transthyretin (ATTR) amyloidosis is a progressive protein misfolding disease with
frequent cardiac involvement. This review aims to determine the value of PET in diagnosis …
frequent cardiac involvement. This review aims to determine the value of PET in diagnosis …
Coronary artery calcification: current concepts and clinical implications
C Onnis, R Virmani, K Kawai, V Nardi, A Lerman… - Circulation, 2024 - Am Heart Assoc
Coronary artery calcification (CAC) accompanies the development of advanced
atherosclerosis. Its role in atherosclerosis holds great interest because the presence and …
atherosclerosis. Its role in atherosclerosis holds great interest because the presence and …
Latent coronary plaque morphology from computed tomography angiography, molecular disease activity on positron emission tomography, and clinical outcomes
Background: Assessments of coronary disease activity with 18F-sodium fluoride positron
emission tomography and radiomics-based precision coronary plaque phenotyping derived …
emission tomography and radiomics-based precision coronary plaque phenotyping derived …
Noninvasive in vivo coronary artery thrombus imaging
Background The diagnosis and management of myocardial infarction are increasingly
complex, and establishing the presence of intracoronary thrombosis has major implications …
complex, and establishing the presence of intracoronary thrombosis has major implications …
Recent advances in cardiovascular diseases research using animal models and PET radioisotope tracers
W Wargocka-Matuszewska, W Uhrynowski… - International Journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVD) is a collective term describing a range of conditions that
affect the heart and blood vessels. Due to the varied nature of the disorders, distinguishing …
affect the heart and blood vessels. Due to the varied nature of the disorders, distinguishing …
Radiotracers to address unmet clinical needs in cardiovascular imaging, part 2: inflammation, fibrosis, thrombosis, calcification, and amyloidosis imaging
Cardiovascular imaging is evolving in response to systemwide trends toward molecular
characterization and personalized therapies. The development of new radiotracers for PET …
characterization and personalized therapies. The development of new radiotracers for PET …
Vessel-by-vessel analysis of lower extremity 18F-NaF PET/CT imaging quantifies diabetes- and chronic kidney disease-induced active microcalcification in patients …
TH Chou, ET Rimmerman, S Patel, MK Wynveen… - EJNMMI research, 2023 - Springer
Background Positron emission tomography (PET)/computed tomography (CT) imaging with
fluorine-18 (18F)-sodium fluoride (NaF) provides assessment of active vascular …
fluorine-18 (18F)-sodium fluoride (NaF) provides assessment of active vascular …
HAP-multitag, a PET and positive MRI contrast nanotracer for the longitudinal characterization of vascular calcifications in atherosclerosis
J Pellico, I Fernández-Barahona… - … Applied Materials & …, 2021 - ACS Publications
Vascular microcalcifications are associated with atherosclerosis plaque instability and,
therefore, to increased mortality. Because of this key role, several imaging probes have …
therefore, to increased mortality. Because of this key role, several imaging probes have …
In Vivo Coronary 18F-Sodium Fluoride Activity: Correlations With Coronary Plaque Histological Vulnerability and Physiological Environment
W Wen, M Gao, M Yun, J Meng, W Yu, Z Zhu… - Cardiovascular …, 2023 - jacc.org
Abstract Background 18F-sodium fluoride (18F-NaF) positron emission tomography
(PET)/computed tomography (CT) is a promising new approach for assessing …
(PET)/computed tomography (CT) is a promising new approach for assessing …