The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Z Zhang, M Kang, H Tan, N Song, M Li, P Xiao… - Chemical Society …, 2022 - pubs.rsc.org
Photo-driven theranostics, also known as phototheranostics, relying on the diverse excited-
state energy conversions of theranostic agents upon photoexcitation represents a significant …

Emerging strategies in enhancing singlet oxygen generation of nano-photosensitizers toward advanced phototherapy

M Tavakkoli Yaraki, B Liu, YN Tan - Nano-Micro Letters, 2022 - Springer
The great promise of photodynamic therapy (PDT) has thrusted the rapid progress of
developing highly effective photosensitizers (PS) in killing cancerous cells and bacteria. To …

Activatable fluorescent probes for real-time imaging-guided tumor therapy

QJ Duan, ZY Zhao, YJ Zhang, L Fu, YY Yuan… - Advanced Drug Delivery …, 2023 - Elsevier
Surgery and drug therapy are the two principal options for cancer treatment. However, their
clinical benefits are hindered by the difficulty of accurate location of the tumors and timely …

Activatable nano-photosensitizers for precise photodynamic cancer therapy

Z Li, Z Zhou, Y Wang, J Wang, L Zhou… - Coordination Chemistry …, 2023 - Elsevier
Owing to the excellent cell ablation ability and low side effects, photodynamic therapy (PDT)
plays an important role in disease treatment, especially cancer. However, most PDT agents …

Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Fluorogenic probes for disease-relevant enzymes

J Zhang, X Chai, XP He, HJ Kim, J Yoon… - Chemical Society …, 2019 - pubs.rsc.org
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Activity‐based smart AIEgens for detection, bioimaging, and therapeutics: Recent progress and outlook

H Li, H Kim, J Han, VN Nguyen, X Peng, J Yoon - Aggregate, 2021 - Wiley Online Library
Activity‐based approaches for designing AIEgens possess prominent advantages including
high selectivity, sensitivity, and signal‐to‐noise ratio, and they have received more attention …

AIE luminogens for bioimaging and theranostics: from organelles to animals

J Qian, BZ Tang - Chem, 2017 - cell.com
High-quality fluorescence bioimaging requires organic exogenous contrast agents with
biocompatibility, brightness, and photostability. The recently discovered and rapidly …

Activatable photosensitizers: agents for selective photodynamic therapy

X Li, S Kolemen, J Yoon… - Advanced Functional …, 2017 - Wiley Online Library
Recent developments in the design of bifunctional and activatable photosensitizers
rejuvenate the aging field of photodynamic sensitization and photodynamic therapy. While …

Two-photon excitation nanoparticles for photodynamic therapy

Y Shen, AJ Shuhendler, D Ye, JJ Xu… - Chemical Society …, 2016 - pubs.rsc.org
Two-photon excitation (TPE) nanoparticle-based photosensitizers (PSs) that combine the
advantages of TPE and nanotechnology have emerged as attractive therapeutic agents for …