The day of extubation is a critical time during an intensive care unit (ICU) stay. Extubation is
usually decided after a weaning readiness test involving spontaneous breathing on a T …

Background Extubation failure is an important issue in ventilated patients and its risk factors
remain a matter of research. We conducted a systematic review and meta-analysis to …

The use of pulmonary artery catheters has diminished, so that other technologies are
emerging. Central venous oxygen saturation measurement (ScvO2) as a surrogate for mixed …

Shock is defined as global tissue hypoxia secondary to an imbalance between systemic
oxygen delivery and oxygen demand. Venous oxygen saturations represent this relationship …

Introduction The concept of weaning-induced cardiac dysfunction emerged 26 years ago
with the publication of a clinical study conducted by François Lemaire and collaborators …

Failed extubation (FE), defined as reintubation 48 or 72 hours after planned extubation,
occurs in a significant percentage of patients and is associated with a substantial burden of …

Background: Active mobilization is a key component in fast-track surgical strategies.
Following major surgery, clinicians are often reluctant to mobilize patients arguing that …

Background High-flow nasal oxygen cannula (HFNC) and noninvasive mechanical
ventilation (NIV) can prevent reintubation in critically ill patients. However, their efficacy in …

Mixed and central venous oxygen saturations are commonly used to ascertain the degree of
systemic oxygenation in critically ill patients. This review examines the physiological basis …

PURPOSE: The purpose of this study was to evaluate prediction factors for extubation failure
(need for reintubation within 48 hours) in medical intensive care unit patients. MATERIALS …