Molecular chess? Hallmarks of anti-cancer drug resistance
IA Cree, P Charlton - BMC cancer, 2017 - Springer
Background The development of resistance is a problem shared by both classical
chemotherapy and targeted therapy. Patients may respond well at first, but relapse is …
chemotherapy and targeted therapy. Patients may respond well at first, but relapse is …
Anti‐cancer therapies of 21st century: novel approach to treat human cancers using cold atmospheric plasma
EA Ratovitski, X Cheng, D Yan… - Plasma Processes …, 2014 - Wiley Online Library
Cold atmospheric plasma (CAP) has just recently been showing promising anti‐cancer
activities supported by ability to induce cell death via apoptosis and cell cycle arrest leading …
activities supported by ability to induce cell death via apoptosis and cell cycle arrest leading …
Anticancer activity of seaweeds
AG Gutiérrez-Rodríguez, C Juarez-Portilla… - Drug Discovery …, 2018 - Elsevier
Highlights•Anti-cancer activity of seaweeds has been probed in numerous studies.•Total
growth inhibition is a good parameter to evaluate seaweeds' activity.•We propose the …
growth inhibition is a good parameter to evaluate seaweeds' activity.•We propose the …
Modulation of apoptosis by melatonin for improving cancer treatment efficiency: An updated review
Radio-and chemotherapy are the most common cancer treatment modalities. They cause
acute and late side effects on normal tissues, which is a burden for delivery of a high dose of …
acute and late side effects on normal tissues, which is a burden for delivery of a high dose of …
Insights of crosstalk between p53 protein and the MKK3/MKK6/p38 MAPK signaling pathway in cancer
L Stramucci, A Pranteda, G Bossi - Cancers, 2018 - mdpi.com
TP53 is universally recognized as a pivotal protein in cell-cycle fate and apoptotic induction
and, unsurprisingly, it is one of the most commonly hijacked control mechanisms in cancer …
and, unsurprisingly, it is one of the most commonly hijacked control mechanisms in cancer …
Therapeutic potential of p53 reactivation in prostate cancer: Strategies and opportunities
Metastatic prostate cancer (mCaP) remains one of the leading causes of cancer-related
death in men worldwide. Androgen receptor (AR) drives the progression of most of the …
death in men worldwide. Androgen receptor (AR) drives the progression of most of the …
Potential role of p53 deregulation in modulating immune responses in human malignancies: A paradigm to develop immunotherapy
S Chauhan, S Jaiswal, V Jakhmola, B Singh… - Cancer Letters, 2024 - Elsevier
The crucial role played by the oncogenic expression of TP53, stemming from mutation or
amyloid formation, in various human malignancies has been extensively studied over the …
amyloid formation, in various human malignancies has been extensively studied over the …
Induction of p53-independent apoptosis and G1 cell cycle arrest by fucoidan in HCT116 human colorectal carcinoma cells
HY Park, SH Park, JW Jeong, D Yoon, MH Han… - Marine drugs, 2017 - mdpi.com
It is well known that fucoidan, a natural sulfated polysaccharide present in various brown
algae, mediates anticancer effects through the induction of cell cycle arrest and apoptosis …
algae, mediates anticancer effects through the induction of cell cycle arrest and apoptosis …
Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy
B Song, P Yang, S Zhang - Cancer Communications, 2024 - Wiley Online Library
Cancer is a leading cause of death worldwide. Targeted therapies aimed at key oncogenic
driver mutations in combination with chemotherapy and radiotherapy as well as …
driver mutations in combination with chemotherapy and radiotherapy as well as …
Recent findings on the role of wild-type and mutant p53 in cancer development and therapy
The p53 protein is a tumor suppressor encoded by the TP53 gene and consists of 393
amino acids with four main functional domains. This protein responds to various cellular …
amino acids with four main functional domains. This protein responds to various cellular …