Calcitonin gene-related peptide: physiology and pathophysiology
FA Russell, R King, SJ Smillie, X Kodji… - Physiological …, 2014 - journals.physiology.org
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …
The noncanonical pathway for in vivo nitric oxide generation: the nitrate-nitrite-nitric oxide pathway
In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …
H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO–TRPA1–CGRP signalling pathway
M Eberhardt, M Dux, B Namer, J Miljkovic… - Nature …, 2014 - nature.com
Nitroxyl (HNO) is a redox sibling of nitric oxide (NO) that targets distinct signalling pathways
with pharmacological endpoints of high significance in the treatment of heart failure …
with pharmacological endpoints of high significance in the treatment of heart failure …
Treatments targeting inotropy: a position paper of the Committees on Translational Research and Acute Heart Failure of the Heart Failure Association of the European …
Acute heart failure (HF) and in particular, cardiogenic shock are associated with high
morbidity and mortality. A therapeutic dilemma is that the use of positive inotropic agents …
morbidity and mortality. A therapeutic dilemma is that the use of positive inotropic agents …
Nitric oxide: what's new to NO?
K Ghimire, HM Altmann, AC Straub… - American Journal of …, 2017 - journals.physiology.org
Nitric oxide (NO) is one of the critical components of the vasculature, regulating key
signaling pathways in health. In macrovessels, NO functions to suppress cell inflammation …
signaling pathways in health. In macrovessels, NO functions to suppress cell inflammation …
H2S and its role in redox signaling
O Kabil, N Motl, R Banerjee - Biochimica et Biophysica Acta (BBA)-Proteins …, 2014 - Elsevier
Hydrogen sulfide (H 2 S) has emerged as an important gaseous signaling molecule that is
produced endogenously by enzymes in the sulfur metabolic network. H 2 S exerts its effects …
produced endogenously by enzymes in the sulfur metabolic network. H 2 S exerts its effects …
The reduction potential of nitric oxide (NO) and its importance to NO biochemistry
MD Bartberger, W Liu, E Ford… - Proceedings of the …, 2002 - National Acad Sciences
A potential of about− 0.8 (±0.2) V (at 1 M versus normal hydrogen electrode) for the
reduction of nitric oxide (NO) to its one-electron reduced species, nitroxyl anion (3NO−) has …
reduction of nitric oxide (NO) to its one-electron reduced species, nitroxyl anion (3NO−) has …
Positive inotropic and lusitropic effects of HNO/NO− in failing hearts: Independence from β-adrenergic signaling
N Paolocci, T Katori, HC Champion… - Proceedings of the …, 2003 - National Acad Sciences
Nitroxyl anion (HNO/NO−), the one-electron reduced form of nitric oxide (NO), induces
positive cardiac inotropy and selective venodilation in the normal in vivo circulation. Here we …
positive cardiac inotropy and selective venodilation in the normal in vivo circulation. Here we …
A fast and selective near-infrared fluorescent sensor for multicolor imaging of biological nitroxyl (HNO)
AT Wrobel, TC Johnstone, A Deliz Liang… - Journal of the …, 2014 - ACS Publications
The first near-infrared fluorescent turn-on sensor for the detection of nitroxyl (HNO), the one-
electron reduced form of nitric oxide (NO), is reported. The new copper-based probe …
electron reduced form of nitric oxide (NO), is reported. The new copper-based probe …
The chemistry of nitroxyl (HNO) and implications in biology
KM Miranda - Coordination Chemistry Reviews, 2005 - Elsevier
Over the past century, HNO research has evolved from fundamental physical examinations
to elucidation of interactions in atmospheric, industrial and bacterial processes. Most …
to elucidation of interactions in atmospheric, industrial and bacterial processes. Most …