Neurovascular unit: a critical role in ischemic stroke

L Wang, X Xiong, L Zhang… - CNS Neuroscience & …, 2021 - Wiley Online Library
Ischemic stroke (IS), a common cerebrovascular disease, results from a sudden blockage of
a blood vessel in the brain, thereby restricting blood supply to the area in question, and …

Neural stem cell therapy for subacute and chronic ischemic stroke

AC Boese, QSE Le, D Pham, MH Hamblin… - Stem cell research & …, 2018 - Springer
Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …

Role of pericytes in skeletal muscle regeneration and fat accumulation

A Birbrair, T Zhang, ZM Wang, ML Messi… - Stem cells and …, 2013 - liebertpub.com
Stem cells ensure tissue regeneration, while overgrowth of adipogenic cells may
compromise organ recovery and impair function. In myopathies and muscle atrophy …

Pericytes at the intersection between tissue regeneration and pathology

A Birbrair, T Zhang, ZM Wang, ML Messi… - Clinical …, 2015 - portlandpress.com
Perivascular multipotent cells, pericytes, contribute to the generation and repair of various
tissues in response to injury. They are heterogeneous in their morphology, distribution …

Brain vascular pericytes following ischemia have multipotential stem cell activity to differentiate into neural and vascular lineage cells

T Nakagomi, S Kubo, A Nakano‐Doi, R Sakuma… - Stem …, 2015 - academic.oup.com
Brain vascular pericytes (PCs) are a key component of the blood‐brain barrier
(BBB)/neurovascular unit, along with neural and endothelial cells. Besides their crucial role …

Pericytes, mesenchymal stem cells and their contributions to tissue repair

SP Wong, JE Rowley, AN Redpath, JD Tilman… - Pharmacology & …, 2015 - Elsevier
Regenerative medicine using mesenchymal stem cells for the purposes of tissue repair has
garnered considerable public attention due to the potential of returning tissues and organs …

Brain pericytes serve as microglia-generating multipotent vascular stem cells following ischemic stroke

R Sakuma, M Kawahara, A Nakano-Doi… - Journal of …, 2016 - Springer
Background Microglia are the resident macrophage population of the central nervous
system (CNS) and play essential roles, particularly in inflammation-mediated pathological …

[HTML][HTML] Skeletal muscle pericyte subtypes differ in their differentiation potential

A Birbrair, T Zhang, ZM Wang, ML Messi… - Stem cell …, 2013 - Elsevier
Neural progenitor cells have been proposed as a therapy for central nervous system
disorders, including neurodegenerative diseases and trauma injuries, however their …

Telocytes in regenerative medicine

Y Bei, F Wang, C Yang, J Xiao - Journal of cellular and …, 2015 - Wiley Online Library
Telocytes (TC s) are a distinct type of interstitial cells characterized by a small cell body and
extremely long and thin telopodes (Tps). The presence of TC s has been documented in …

[HTML][HTML] Meninges: from protective membrane to stem cell niche

I Decimo, G Fumagalli, V Berton… - American journal of …, 2012 - ncbi.nlm.nih.gov
Meninges are a three tissue membrane primarily known as coverings of the brain. More in
depth studies on meningeal function and ultrastructure have recently changed the view of …