Expert consensus recommendations for the suspicion and diagnosis of transthyretin cardiac amyloidosis
Cardiomyopathy is a manifestation of transthyretin amyloidosis (ATTR), which is an
underrecognized systemic disease whereby the transthyretin protein misfolds to form fibrils …
underrecognized systemic disease whereby the transthyretin protein misfolds to form fibrils …
ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: part 1 of 2—evidence base …
S Dorbala, Y Ando, S Bokhari… - Circulation …, 2021 - Am Heart Assoc
Sharmila Dorbala, MD, MPH, FASNC, Chair*; Yukio Ando, MD, PhD†; Sabahat Bokhari,
MD‡; Angela Dispenzieri, MD § ; Rodney H. Falk, MD*; Victor A. Ferrari, MD∥; Marianna …
MD‡; Angela Dispenzieri, MD § ; Rodney H. Falk, MD*; Victor A. Ferrari, MD∥; Marianna …
Systemic amyloidosis
Tissue deposition of protein fibrils causes a group of rare diseases called systemic
amyloidoses. This Seminar focuses on changes in their epidemiology, the current approach …
amyloidoses. This Seminar focuses on changes in their epidemiology, the current approach …
How to image cardiac amyloidosis: a practical approach
Cardiac amyloidosis (CA) is one of the most rapidly progressive forms of heart disease, with
a median survival from diagnosis, if untreated, ranging from< 6 months for light chain …
a median survival from diagnosis, if untreated, ranging from< 6 months for light chain …
Targeting protein aggregation for the treatment of degenerative diseases
YS Eisele, C Monteiro, C Fearns… - Nature reviews Drug …, 2015 - nature.com
The aggregation of specific proteins is hypothesized to underlie several degenerative
diseases, which are collectively known as amyloid disorders. However, the mechanistic …
diseases, which are collectively known as amyloid disorders. However, the mechanistic …
Procedural recommendations of cardiac PET/CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation (4Is)-related cardiovascular …
RHJA Slart, AWJM Glaudemans, O Gheysens… - European journal of …, 2021 - Springer
With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in
cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with …
cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with …
Myocardial amyloidosis: the exemplar interstitial disease
Cardiac involvement drives prognosis and treatment choices in cardiac amyloidosis.
Echocardiography is the first-line examination for patients presenting with heart failure, and …
Echocardiography is the first-line examination for patients presenting with heart failure, and …
Diagnostic imaging of cardiac amyloidosis
A Martinez-Naharro, AJ Baksi, PN Hawkins… - Nature Reviews …, 2020 - nature.com
Systemic amyloidosis encompasses a debilitating, under-diagnosed but increasingly
recognized group of disorders characterized by the extracellular deposition of misfolded …
recognized group of disorders characterized by the extracellular deposition of misfolded …
Imaging cardiac amyloidosis: a pilot study using 18F-florbetapir positron emission tomography
S Dorbala, D Vangala, J Semer, C Strader… - European journal of …, 2014 - Springer
Purpose Cardiac amyloidosis, a restrictive heart disease with high mortality and morbidity, is
underdiagnosed due to limited targeted diagnostic imaging. The primary aim of this study …
underdiagnosed due to limited targeted diagnostic imaging. The primary aim of this study …
Light-chain cardiac amyloidosis: strategies to promote early diagnosis and cardiac response
M Grogan, A Dispenzieri, MA Gertz - Heart, 2017 - heart.bmj.com
Amyloid light chain (AL) amyloidosis is a systemic disease characterised by the aggregation
of misfolded immunoglobulin light chain (LC), predominantly in the heart and kidneys …
of misfolded immunoglobulin light chain (LC), predominantly in the heart and kidneys …