Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

A Aslan, C Aslan, NM Zolbanin, R Jafari - Pneumonia, 2021 - Springer
COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress
syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even …

The role of NO in COVID-19 and potential therapeutic strategies

W Fang, J Jiang, L Su, T Shu, H Liu, S Lai… - Free radical biology and …, 2021 - Elsevier
Nitric oxide (NO) is a free radical playing an important pathophysiological role in
cardiovascular and immune systems. Recent studies reported that NO levels were …

Pharmacological treatments of COVID-19

A Sahebnasagh, R Avan, F Saghafi… - Pharmacological …, 2020 - Springer
The viral infection due to the new coronavirus or coronavirus disease 2019 (COVID-19),
which was reported for the first time in December 2019, was named by the World Health …

Inhaled nitric oxide in mechanically ventilated patients with COVID-19

M Ferrari, A Santini, A Protti, DT Andreis… - Journal of Critical …, 2020 - Elsevier
2. Methods As part of our routine clinical practice for ARDS, we administered a 30-min test
dose of 20 ppm to ten adults with COVID-19 treated with invasive mechanical ventilation and …

Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms

MR Garren, M Ashcraft, Y Qian, M Douglass… - Applied materials …, 2021 - Elsevier
Nitric oxide (NO) is a gasotransmitter of great significance to developing the innate immune
response to many bacterial and viral infections, while also modulating vascular physiology …

Nitric oxide inhalation as an interventional rescue therapy for COVID-19-induced acute respiratory distress syndrome

J Kobayashi, I Murata - Annals of Intensive Care, 2020 - Springer
COVID-19 is an emerging disease of public health concern. While there is no specific
recommended treatment for COVID-19, nitric oxide has the potential to be of therapeutic …

Rescue therapy with inhaled nitric oxide and almitrine in COVID-19 patients with severe acute respiratory distress syndrome

F Bagate, S Tuffet, P Masi, F Perier, K Razazi… - Annals of intensive …, 2020 - Springer
Background In COVID-19 patients with severe acute respiratory distress syndrome (ARDS),
the relatively preserved respiratory system compliance despite severe hypoxemia, with …

[HTML][HTML] Nitric oxide (NO) and nanoparticles–potential small tools for the war against COVID-19 and other human coronavirus infections

JC Pieretti, O Rubilar, RB Weller, GR Tortella… - Virus research, 2021 - Elsevier
The endogenous free radical nitric oxide (NO) plays a pivotal role in the immunological
system. NO has already been reported as a potential candidate for use in the treatment of …

Nitric oxide: clinical applications in critically ill patients

S Redaelli, A Magliocca, R Malhotra, G Ristagno… - Nitric Oxide, 2022 - Elsevier
Inhaled nitric oxide (iNO) acts as a selective pulmonary vasodilator and it is currently
approved by the FDA for the treatment of persistent pulmonary hypertension of the newborn …

Right ventricular strain is common in intubated COVID-19 patients and does not reflect severity of respiratory illness

LE Gibson, RD Fenza, M Lang… - Journal of intensive …, 2021 - journals.sagepub.com
Background: Right ventricular (RV) dysfunction is common and associated with worse
outcomes in patients with coronavirus disease 2019 (COVID-19). In non-COVID-19 acute …