The repertoire of naturally presented peptides within the MHC (major histocompatibility
complex) or HLA (human leukocyte antigens) system on the cellular surface of every …

Hepatocellular carcinoma (HCC) is highly heterogeneous in nature and has been one of the
most common cancer types worldwide. To ensure repeatability of identified gene expression …

High-throughput sequencing has ushered in a diversity of approaches for identifying genetic
variants and understanding genome structure and function. When applied to individuals with …

Accelerating cures for children with cancer remains an immediate challenge as a result of
extensive oncogenic heterogeneity between and within histologies, distinct molecular …

Human complex traits and common diseases show tissue-and cell-type-specificity. Recently,
single-cell RNA sequencing (scRNA-seq) technology has successfully depicted cellular …

Single-cell RNA sequencing (scRNA-Seq) is rapidly becoming a powerful tool for high-
throughput transcriptomic analysis of cell states and dynamics at the single cell level. Both …

Although there has been great progress in cancer treatment, cancer remains a serious
health threat to humans because of the lack of biomarkers for diagnosis, especially for early …

Protein–protein interactions (PPIs) are crucial to mediate biological functions, and
understanding PPIs in cancer type-specific context could help decipher the underlying …

Extracellular vesicles (EVs) are membrane-enclosed particles that play an important role in
cancer progression and have emerged as a promising source of circulating biomarkers …

Although circulating tumor cells (CTCs) have shown promise as potential biomarkers for
diagnostic and prognostic assessment in gastric cancer (GC), determining the predictive and …