Actinomycetes benefaction role in soil and plant health

AA Bhatti, S Haq, RA Bhat - Microbial pathogenesis, 2017 - Elsevier
Actinomycetes are aerobic, spore forming gram-positive bacteria, belonging to the order
actinomycetales characterized with substrate and aerial mycelium growth. They are the most …

Gifted microbes for genome mining and natural product discovery

RH Baltz - Journal of Industrial Microbiology and Biotechnology, 2017 - academic.oup.com
Actinomycetes are historically important sources for secondary metabolites (SMs) with
applications in human medicine, animal health, and plant crop protection. It is now clear that …

Streptomyces species: Ideal chassis for natural product discovery and overproduction

R Liu, Z Deng, T Liu - Metabolic engineering, 2018 - Elsevier
There is considerable interest in mining organisms for new natural products (NPs) and in
improving methods to overproduce valuable NPs. Because of the rapid development of tools …

An overview on transcriptional regulators in Streptomyces

A Romero-Rodríguez, I Robledo-Casados… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Streptomyces are Gram-positive microorganisms able to adapt and respond to different
environmental conditions. It is the largest genus of Actinobacteria comprising over 900 …

Diversity and versatility of actinomycetes and its role in antibiotic production

HS Chaudhary, B Soni, AR Shrivastava… - Journal of Applied …, 2013 - japsonline.com
This review summarizes about the actinomycetes and their capability to produce bioactive
secondary metabolites, many of which have been successfully isolated and turned into …

Next generation sequencing of actinobacteria for the discovery of novel natural products

JP Gomez-Escribano, S Alt, MJ Bibb - Marine drugs, 2016 - mdpi.com
Like many fields of the biosciences, actinomycete natural products research has been
revolutionised by next-generation DNA sequencing (NGS). Hundreds of new genome …

Diversity, mechanisms and beneficial features of phosphate-solubilizing Streptomyces in sustainable agriculture: A review

FE Chouyia, V Ventorino, O Pepe - Frontiers in Plant Science, 2022 - frontiersin.org
Currently, the use of phosphate (P) biofertilizers among many bioformulations has attracted
a large amount of interest for sustainable agriculture. By acting as growth promoters …

Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies

J Ossai, B Khatabi, SE Nybo… - Journal of applied …, 2022 - Wiley Online Library
Actinomycetes are prolific sources of bioactive molecules. Traditional workflows including
bacterial isolation, fermentation, metabolite identification and structure elucidation have …

Molecular and therapeutic insights of rapamycin: a multi-faceted drug from Streptomyces hygroscopicus

SK Ganesh, C Subathra Devi - Molecular biology reports, 2023 - Springer
The advancement in pharmaceutical research has led to the discovery and development of
new combinatorial life-saving drugs. Rapamycin is a macrolide compound produced from …

[HTML][HTML] Rational synthetic pathway refactoring of natural products biosynthesis in actinobacteria

GY Tan, T Liu - Metabolic engineering, 2017 - Elsevier
Natural products (NPs) and their derivatives are widely used as frontline treatments for many
diseases. Actinobacteria spp. are used to produce most of NP antibiotics and have also …